沙参麦冬汤治疗急性气管支气管炎临床观察

Effectiveness Observation of Shashen Maidong Decoction of TCM in Acute Tracheobronchitis

目的:观察沙参麦冬汤加减治疗急性气管支气管炎的临床疗效。方法:选择50例急性气管支气管炎患者,随机分为对照组与研究组各25例,对照组采取常规西药治疗,研究组采取沙参麦冬汤加减治疗,对比两组临床效果。结果:对照组总有效率64.00%,明显低于研究组总有效率92.00%(P<0.05);治疗前两组白细胞介素-1(IL-1)、白细胞介素-6(IL-6)以及肿瘤坏死因子-a(TNF-a)水平无统计学差异(P>0.05),治疗后研究组各指标水平低于对照组(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:急性气管支气管炎患者采取沙参麦冬汤治疗效果较好,可有效缓解患者临床症状,促进炎症的消退,不良反应较低。

Objective To observe the clinical effect of Shashen Maidong decoction in the treatment of acute tracheobronchial bronchitis. Methods 50 patients with acute tracheobronchitis were selected. The subjects were randomly assigned to study group and control group,25 cases each group. The control group took the western medicine; the study group took the modified TCM therapy of Shashen Maidong Decoction. The therapeutic effect was compared. Results The total effective rate in the control group（ 64. 00%） was significantly lower than study group（ 92. 00%）（ P〈 0. 05）; before treatment,the interleukin-1（ IL-1）,interleukin-6（ IL-6） and tumor necrosis factor-a（ TNF-a） for two groups were not significantly different（ P 〉0. 05）; after treatment,the related index for study group were lower than control group（ P 〈0. 05）; the adverse event rate for two groups was not significantly different（ P 〉0. 05）. Conclusion The Shashen Maidong Decoction of TCM has an obvious effect in acute tracheobronchitis patients,can effectively relieve the clinical symptoms of patients,promote the regression of inflammation,and lower adverse reactions.