我院2017年中成药注射液不良反应的调查结果及改进对策

Investigation results and improvement measures of adverse reactions of Chinese patent medicine injection in our hospital during 2017

目的调查我院2017年中成药注射液不良反应发生情况,对调查结果进行分析并探讨改进对策。方法回顾性分析我院62例中成药注射液不良反应报告资料,统计发生不良反应患者的性别、年龄、不良反应出现时间、所涉及药品种类、累及器官及表现,并探讨改进对策。结果 62例中成药注射液不良反应报告中,男女性占比分别为53.23%和46.77%,中成药注射液不良反应发生率最高的年龄段为≥60岁,其次为50~59岁及0~9岁。药物不良反应主要发生在用药后30 min内,以活血化瘀类药物多见。不良反应主要累及皮肤及附件组织。结论中成药注射液的不良反应较为常见,在临床应用过程中应加强合理用药。

Objective To investigate the incidences of adverse reactions of Chinese patent medicine injection in ourhospital during 2017, the investigation results were analyzed and improvement measures were discussed. Methods A totalof 62 cases of adverse reactions reports of Chinese patent medicine injection in our hospital were retrospectivelyanalyzed. The gender, age of patients with adverse reactions, the time of adverse reactions occurrence, the types ofinvolved drugs, the involved organs and the manifestations of the adverse reactions were counted, and the improvementmeasures were discussed. Results There were 62 cases of adverse reactions reports caused by Chinese patent medicineinjection in our hospital. The ratios of male and female were 53.23% and 46.77% respectively. The age group with thehighest incidence of adverse reactions of Chinese patent medicine injection was ≥60 years old, followed by 50-59 yearsold and 0-9 years old. The adverse reactions were mainly happened within 30 min after administration. The main type ofdrugs involved in adverse reactions were mainly activating blood and removing phlegm drugs. The adverse reactionsmainly involved in skin and accessory tissues. Conclusion The adverse reactions of Chinese patent medicine injection arevery common in the clinical application process, we should strengthen the rational use of drugs.