简易水扩张治疗女性难治性膀胱过度活动症的效果

Efficacy of simple bladder hydrodistention in treatment for female refractory overactive bladder

目的评价膀胱简易水扩张对女性难治性膀胱过度活动症的治疗效果。方法收集咸阳市中心医院2015年2月~2017年8月收治的女性难治性膀胱过度活动症患者62例,随机数字表法分为膀胱简易水扩张观察组和辣椒辣素对照组,每组各31例。观察指标:膀胱过度活动症症状评分表(OABSS)评分、日均排尿次数、夜尿次数、平均每次排尿量、初始尿意容量、最大膀胱容量。结果两组治疗后OABSS评分、日均排尿次数、夜尿次数、每次排尿量、初始尿意容量、最大膀胱容量与治疗前比较,差异均有统计学意义(P<0.05)。治疗后1周,观察组在夜尿次数、日均每次排尿量、初始尿意容积、最大膀胱容量与对照组比较,差异有统计学意义(P<0.05)。治疗后3个月,两组日均排尿次数、最大膀胱容量比较,差异有统计学意义(P<0.05)。观察组与对照组临床治疗有效率比较,差异无统计学意义(P>0.05)。结论膀胱简易水扩张可以作为难治性膀胱过度活动症的一个治疗方法的补充。

Objective To evaluate the efficacy of simple bladder hydrodistention to treat female refractory overactive bladder. Methods Sixty-two female patients with refractory overactive bladder treated in Xianyang Central Hospital from February 2015 to August 2017 were selected and they were divided into simple bladder hydrodistention group（observation group） and Capsaicin（CAP） group（control group）, with 31 cases in each group. OABSS scores, daily voiding frequency, urinary frequency in night, quantity of each urination, bladder capacity at first desire, maxima bladder capacity were recorded. Results OABSS scores, daily voiding frequency, urinary frequency in night, average quantity of each urination, bladder capacity at first desire, maxima bladder capacity after treatment in the two groups had difference with those before treatment（P〈0.05）. One 1 week after treatment, urinary frequency in night, average quantity of each urination, bladder capacity at first desire, maxima bladder capacity in the observation group were different from those in the control group（P〈0.05）. Three months treatment after, there were differences in daily voiding frequency and maxima bladder capacity between the two groups, the differences were statistically significant（P〉0.05）. There was no significant difference in clinical treatment efficiency between the two groups（P〉0.05）. Conclusion Simple bladder hydrodistention can be used as a supplement treatment for refractory bladder overactivity.