针刺联合加味温胆汤治疗痰热扰心型失眠的临床研究

Clinical study of acupuncture combined with Modified Wendan Decoction in the treatment of insomnia with syndrome of phlegm-heat attacking heart

目的观察针刺联合加味温胆汤治疗痰热扰心型失眠的临床效果。方法将湖北省中医院精神心理科2016年1月~2017年6月收治的64例痰热扰心型失眠患者按照随机数字表法分为观察组和对照组,每组32例。对照组予口服艾司唑仑片治疗,观察组在对照组治疗的基础上给予针刺联合加味温胆汤治疗。治疗3周后,观察两组治疗前后主要睡眠指标(睡眠潜伏期、入眠效率、总睡眠时间)、匹兹堡睡眠质量指数量表(PSQI)(睡眠效率、入睡时间、睡眠时间、睡眠障碍、日间功能)的变化状况,并比较两组临床疗效。结果观察组治疗后总有效率显著高于对照组,差异有统计学意义(P<0.05)。与治疗前比较,两组治疗后睡眠潜伏期均显著降低(P<0.05),入眠效率和总睡眠时间均显著升高,差异有统计学意义(P<0.05),且观察组治疗后上述睡眠指标改善状况均显著优于对照组,差异有统计学意义(P<0.05);两组治疗后入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能评分均较治疗前显著降低,差异有统计学意义(P<0.05),且观察组治疗后上述PSQI指标评分均显著低于对照组,差异有统计学意义(P<0.05)。结论针刺联合加味温胆汤能够提高痰热扰心型失眠患者的睡眠质量,缓解临床症状。

Objective To observe the clinical effect of acupuncture combined with Modified Wendan Decoction in the treatment of insomnia with syndrome of phlegm-heat attacking heart. Methods According to the random number table method, 64 cases of insomnia patients with syndrome of phlegm-heat attacking heart admitted to Department of Psychiatry, Hubei Hospital of Traditional Chinese Medicine from January 2016 to June 2017 were randomly divided into observation group and control group, with 32 cases in each group. The control group was treated with Estazolam Tablets orally. Based on control group, the observation group was treated with acupuncture combined with Modified Wendan Decoction. After 3 weeks of treatment, the changes of main sleep parameters（sleep latency, sleep efficiency, total sleep time）, Pittsburgh sleep quality index scale（PSQI）（sleep efficiency, fall-sleep time, sleep time, sleep disorder, daytime function） of the two groups before and after treatment were observed, and the clinical effect of the two groups was compared. Results After treatment, the total effective rate of the observation group was significantly higher than that of the control group, the difference was statistically significant（P〈0.05）. Compared with those before treatment, the sleep latency of the two groups was significantly decreased（P〈0.05）, the sleep efficiency and total sleep time were significantly increased, the differences were statistically significant（P〈0.05）, and the improvement of the above sleep indexes in the observation group were all significantly better than those of the control group（P〈0.05）. The scores of fall-sleep time, sleep time, sleep efficiency, sleep disorder, and daytime function in the two groups after treatment were significantly lower than those before treatment, the differences were statistically significant（P〈0.05）, and the scores of PSQI indexes above in the observation group were significantly lower than those of the control group, the differences were statistically significant（P〈0.05）. Conclusion Acupuncture combined with Modified Wendan Decoction can improve the sleep quality of insomnia patients with syndrome of phlegm-heat attacking heart, and relieve clinical symptoms.