中药沐足缓解小儿原发性肾病综合征水肿的疗效观察

Efficacy of Chinese medicine foot-bathing on relieving edema of children primary nephrotic syndrome

目的评价中药沐足对小儿原发性肾病综合征肾性水肿的临床疗效。方法选取2015年10月~2017年6月在广东省中医院(以下简称"我院")儿科住院的肾病综合征肾性水肿患儿60例作为研究对象,采用简单随机分配方法,随机分为治疗组和对照组,每组各30例。两组均给予常规基础治疗及护理干预,治疗组额外接受我院药房提供的中药颗粒剂溶水稀释后进行沐足,每日1次,每次20 min,7 d为1个疗程,共1个疗程。干预后7 d,比较两组患儿凹陷性水肿的程度、尿量、腹围、下肢周径等指标。结果治疗后,两组患儿凹陷性水肿的严重程度均有所减轻,且治疗组的减轻程度优于对照组,差异有统计学意义(P<0.05);治疗后,两组患儿尿量均增加,且治疗组患儿的24 h尿量明显多于对照组,差异有统计学意义(P<0.05);治疗后,两组患儿腹围、下肢周径差异无统计学意义(P>0.05)。结论中药沐足有助于改善原发性肾病综合征患儿的水肿症状,该疗法简便易行,适合于临床实践与推广。

Objective To evaluate the clinical effect of foot-bathing with traditional Chinese medicine on relieving edema of children with primary nephrotic syndrome. Methods Sixty children treated inpatient diagnosed with primary nephrotic syndrome with renal edema in Department of Pediatrics, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine（＂our hospital＂ for short） from October 2015 to June 2017 were selected as subjects.They were divided into control group and treatment group by simple random asignment, with 30 cases in each group.Both groups were given routine treatment and nursing intervention. The treatment group received Chinese herbal（medicine particle prescription in our hospital） foot-bathing treatment for 20 min every day additionally. The course of treatment was 7 days, and both groups were treated for 1 course. Severity of edema, urine volume（24 h）, abdominal circumference and the lower limb circumference were compared between the two groups. Results After treatment,the severity of edema in both groups alleviated, and the degree of reduction in the treatment group was better than that in the control group, the difference was statistically significant（P〈0.05）. After treatment, the 24 h urine volume increased in both groups, and the increase in the treatment group was higher than that in the control group, the difference was statistically significant（P〈0.05）. After treatment, abdominal circumference and lower limb circumference in the two groups had no significant difference（P〉0.05）. Conclusion Chinese medicine foot-bathing was beneficial to alleviate edema. The therapy is simple and convenient that can be applied in clinical practice and promotion.