我院药品不良反应报告分析

Analysis on Adverse Drug Reaction Reporting in Our Hospital

目的:分析我院药品不良反应(ADR)的发生规律和发生特点,为进一步指导临床合理用药提供依据。方法:采用回顾性分析方法,对我院2016年1月~2017年7月收集的528例ADR报告从性别、年龄、发生种类、累及器官、报告人等方面进行统计分析。结果:ADR报告的发生性别无显著性差异,抗菌药物和中药制剂的ADR发生例数最多,占比分别为20.72%和10.74%。抗菌药物中发生ADR例数最多的是喹诺酮类,发生品种数最多的为头孢菌素类。ADR的累及器官以皮肤及其附件最多,占比33.76%。结论:应加强医护人员对不良反应重要性的学习,对婴幼儿及老年人等易发ADR群体在用药过程中严密监护,合理使用抗菌药物,严格规范中药制剂使用过程中的操作规程,尽可能减少ADR的发生。

Objective：To investigate the characteristics of adverse drug reactions （ADR）） m our hospital tor further guiding rational drug use in clinic.Methods： Retrospective analysis was used to analyze 528 cases of ADR reports collected in our hospital from January 2016 to July 2017, including gender, age, kinds of ADRs, involved organs and reporters.Results： There were no significant differences in the sex of ADR reports, and the number of ADR in antihacterial and traditional Chinese medicine preparations was the highest, accounting for 20.72% and 10.74% respectively. Quinolones ale the most common antibiotics in ADR, and cephalosporins have the most species. Most of the involved organs in ADR were skin and accessories, accounting for 33.76%.Conelusios：We should strengthen the importance of adverse drug reaction reporting on medical staff, especially for young children and elderly people.To use the antimierobial drugs rationally and strictly regulate the operation rules of traditional Chinese medicine will reduce the occurrence of ADR as far as possible.