417例急性胰腺炎患者的病因及临床特点分析

Analysis on Etiology and Clinical Features of 417 Patients with Acute Pancreatitis

目的探讨急性胰腺炎(acute pancreatitis,AP)的病因及临床特点。方法分析作者医院2016-01/2018-03月收治的417例AP病例,分别记录患者年龄、性别、病因、胰腺炎临床分型等,根据病因分为胆源性AP(n=196)、高三酰甘油性AP(n=109)、酒精性AP(n=29)、高脂饮食相关性AP(n=35)及其他病因性AP(n=48)共5组。结果各组间平均年龄、男女比例、住院时长、复发性AP比较差异均有统计学意义(P<0.01),各组间不同病因与AP病情轻重程度比较差异无统计学意义(P>0.05)。结论 AP的病因构成在发生变化,胆源性和高三酰甘油血症是AP的主要病因。

Objective To explore the etiology and clinical features of 417 acute pancreatitis（AP）patients.Methods The clinical data of 417 AP patients admitted to authors＇ hospital from January 2016 to March 2018 were reviewed to record the age,sex,etiology,clinical classification of pancreatitis,etc.According to the etiology,all patients were divided into 5 groups：biliary AP group（n=196）,hyperlipidemia AP group（n=109）,alcoholic AP group（n=29）,high-fat diet correlated AP group（n=35）and other etiological AP group（n=35）.Results There were significantly differences in the average age,sex ratio,hospital stay and recurrent AP among all groups（P〈0.01）.No obviously differences were found between different etiology and severity AP among all groups（P〉0.05）.Conclusion The constituents of etiology of AP is changing.Biliary and hyperlipidemia are the main causes of AP.