Study on timing and dosage of acupuncture in stroke treatment

目的:总结针刺治疗中风的时机、剂量与疗效之间的关系。方法:检索有关针刺治疗中风的相关量学临床研究,以针刺量学因素的时间因素和剂量因素为切入点,从针刺前因素、针刺时因素及针刺后因素对针刺时效关系及针刺量效关系进行分层辨析。结果:针刺量学研究论述不一,尤其对于针刺留针时间、两次针刺间隔时间及疗程等时间因素缺乏严格一致的量学界定,但对于针刺治疗中风病的介入时机、针刺时刻以及经穴特异性和针刺手法的量学认识普遍一致。结论:针刺时效、量效研究的核心是针刺最佳刺激量的研究,针刺最佳刺激量是临床获效的关键。

Objective： To summarize the timing-efficacy relationship and the dosage–efficacy relationship of acupuncture in stroke treatment. Method： Literature research was conducted for quantitative clinical studies of acupuncture in stroke treatment, with the entry point on the timing factor and dosage factor. A hierarchical analysis was performed on observing the time–efficacy relationship and the dosage–efficacy relationship before, during and after acupuncture. Results： Though the retrieved studies differ especially in such timing factors as needle retaining time, acupuncture interval and course, they share an agreement in the acupuncture intervention time point, acupuncture timing, specificity of acupoints and acupuncture manipulation. Conclusion： The optimal stimulation is the core of the research on the timing-efficacy relationship and the dosage–efficacy relationship of acupuncture and also the key to the clinical efficacy.