期刊文献+

细胞因子在结直肠癌中的作用及其研究进展 被引量:4

Role of Cytokines in Colorectal Cancer and its Progress in Research
下载PDF
导出
摘要 结直肠癌的发病机制涉及多因素的相互作用,其中免疫因素起有重要作用。固有免疫和适应性免疫产生的大量细胞因子对肿瘤发生、发展起有决定性作用。而肿瘤细胞通过自身适应性变化可改变细胞因子的表达及其作用。本文就细胞因子在结直肠癌发生中的作用及其研究进展作一综述。 The pathogenesis of colorectal cancer involves multi-factorial interaction,and immunity plays an important role. Innate immunity and adaptive immunity produce a large number of cytokines which play a decisive role in tumor development. Meanwhile,tumor cells can change the expression and effect of cytokines via their adaptive changes. This article reviewed the role of cytokines in the development of colorectal cancer and its progress in research.
作者 杨振华 季光 YANG Zhenhua;JI Guang(Department of Digestive Endoscopy,Longhua Hospital,Shanghai University of Traditional Chinese Medicin;Institute of Digestive Diseases,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai(200032)
出处 《胃肠病学》 2018年第8期509-512,共4页 Chinese Journal of Gastroenterology
关键词 细胞因子类 结直肠肿瘤 免疫疗法 Cytokines Colorectal Neoplasms Immunotherapy
  • 相关文献

参考文献2

二级参考文献46

  • 1Fran Balkwill,Alberto Mantovani.Inflammation and cancer: back to Virchow?[J].The Lancet.2001(9255)
  • 2Martin Grimm,Mia Kim,Andreas Rosenwald,Burkhard von Rahden,Igor Tsaur,Eva Meier,Uwe Heemann,Christoph-Thomas Germer,Martin Gasser,Ana Maria Waaga-Gasser.Tumour-mediated TRAIL-Receptor expression indicates effective apoptotic depletion of infiltrating CD8+ immune cells in clinical colorectal cancer[J].European Journal of Cancer.2010(12)
  • 3Wilma E. Mesker,Gerrit-Jan Liefers,Jan M.C. Junggeburt,Gabi W. van Pelt,Paola Alberici,Peter J.K. Kuppen,Noel F. Miranda,Karin A.M. van Leeuwen,Hans Morreau,Karoly Szuhai,Rob A.E.M. Tollenaar,Hans J. Tanke.Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I–II colon cancer patients[J].Cellular Oncology.2009(3)
  • 4Hamdi I. A.Sati,MikeGreaves,Jane F.Apperley,R. Graham G.Russell,Peter I.Croucher.Expression of interleukin‐1β and tumour necrosis factor‐α in plasma cells from patients with multiple myeloma[J].British Journal of Haematology.2001(2)
  • 5Frances Burke,Michele Relf,Rupert Negus,Frances Balkwill.A CYTOKINE PROFILE OF NORMAL AND MALIGNANT OVARY[J].Cytokine.1996(7)
  • 6Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology 2010, 138: 2073-2087.e2073.
  • 7Bergman M, Djaldetti M, Salman H, Bessler H. Inflammation and colorec- tal cancer: does aspirin affect the interaction between cancer and immune cells? Inflammation 2011, 34: 22-28.
  • 8Saleh M, Trinchieri G. Innate immune mechanisms of colitis and colitis-associated colorectal cancer. Nat Rev Immuno12010, 11: 9-20.
  • 9Cappell MS. Pathophysiology, clinical presentation, and management of colon cancer. Gastroenterol Clin North Am 2008, 37: 1-24.
  • 10Erdelyi I, Levenkova N, Lin EY, Pinto JT, Lipkin M, Quimby FW, Holt PR. Western-style diets induce oxidative stress and dysregulate immune re- sponses in the colon in a mouse model of sporadic colon cancer. J Nutr 2009, 139: 2072-2078.

共引文献11

同被引文献39

引证文献4

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部