不稳定型心绞痛治疗药物的临床应用分析

Clinical application analysis of unstable angina pectoris drugs

目的探究不稳定型心绞痛治疗药物的临床应用。方法 86例不稳定型心绞痛患者,按随机数字表法分为对照组和观察组,各43例。对照组患者给予常规治疗,观察组患者给予氯吡格雷联合阿司匹林治疗。比较两组患者的治疗效果、心绞痛发作次数、心绞痛持续时间及用药不良反应发生情况。结果观察组治疗总有效率为93.02%,高于对照组的76.74%,差异具有统计学意义(P<0.05)。观察组患者心绞痛发作次数少于对照组,心绞痛持续时间短于对照组,差异具有统计学意义(P<0.05)。观察组用药不良反应发生率4.65%低于对照组的18.60%,差异具有统计学意义(P<0.05)。结论不稳定型心绞痛采用氯吡格雷联合阿司匹林药物治疗效果显著,能有效提高治疗效果,减少心绞痛发作次数,缩短疼痛时间,用药安全性较高,值得在临床治疗中使用及推广。

Objective To explore the clinical application of unstable angina pectoris drugs. Methods A total of 86 patients with unstable angina pectoris were divided into control group and observation group according to the random number table method, 43 cases in each group. Patients in the control group were given conventional therapy, patients in the observation group were given Clopidogrel combined with Aspirin therapy. The therapeutic effect, angina attack frequency, angina duration and adverse drug reactions were compared between the two groups. Results The total effective rate of the observation group was 93.02%, which was significantly higher than 76.74% of the control group, the difference was statistically significant（P〈0.05）. The attack frequency of angina pectoris in the observation group were significantly less than that in the control group, and the duration of angina pectoris in the observation group was significantly shorter than that in the control group, the differences were statistically significant（P〈0.05）. The incidence of adverse drug reactions in the observation group was 4.65%, which was significantly lower than 18.60% in the control group, the difference was statistically significant（P〈0.05）. Conclusion The treatment effect of Clopidogrel combined with Aspirin in the treatment of unstable angina pectoris is significant. It can effectively improve the therapeutic effect, reduce the attack frequency of angina pectoris, shorten the pain time, with higher drug safety, is worthy of clinical application and promotion.