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脾氨肽联合小剂量罗红霉素治疗支气管扩张稳定期患者效果观察 被引量:4

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摘要 目的观察脾氨肽联合小剂量罗红霉素治疗支气管扩张稳定期患者的临床效果。方法选取2016年8月至2017年7月鄢陵县疾病预防控制中心86例支气管扩张稳定期患者,采用随机数表法分为两组,各43例。对照组接受常规治疗,观察组在对照组基础上接受脾氨肽联合小剂量罗红霉素治疗。治疗前后对比两组肺功能[1 s呼气量(FEV1)、FEV1/用力肺活量(FEV1/FVC)]及免疫功能(CD4+、CD8+),采用呼吸困难指数(m MRC)分级评估对比治疗前后两组呼吸状况。结果治疗后观察组FEV1、FEV1/FVC、CD4+均高于对照组,CD8+低于对照组,差异有统计学意义(P<0.05);治疗后观察组m MRC分级低于对照组,差异有统计学意义(P<0.05)。结论脾氨肽联合小剂量罗红霉素治疗支气管扩张稳定期患者可增强其肺功能及免疫功能,改善呼吸情况。
作者 晋俊辉
出处 《河南医学研究》 CAS 2018年第12期2239-2240,共2页 Henan Medical Research
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