鼻咽癌同期放化疗患者生活质量调查

Quality of life in patients with nasopharyngeal carcinoma treated with concurrent chemoradiotherapy

目的通过评价同期放化疗前后鼻咽癌患者生活质量的变化情况,为治疗提供指导。方法选择2015年3月至2017年10月云浮市人民医院收治的接受同期放化疗的126例鼻咽癌患者。在同期放化疗前及开始治疗后3个月,采用欧洲癌症研究与治疗组织开发的生活质量核心量表进行生活质量评定。结果治疗后,患者整体健康状况评分高于治疗前,功能领域评分高于治疗前,症状领域评分中,疲劳、恶心呕吐、疼痛、食欲丧失、经济压力方面评分高于治疗前,差异有统计学意义(P<0.05)。结论鼻咽癌患者经过同期放化疗后,整体生活质量下降,尤其在疲劳、恶心呕吐、疼痛、食欲丧失、经济压力等方面下降明显。

Objective To provide guidance for treatment by evaluating the changes in quality- of life of patients with nasopha- ryngeal carcinoma before and after concurrent radiotherapy and chemotherapy. Methods A total of 126 patients with nasopharyn- geal carcinoma who underwent concurrent ehemoradiotherapy were enrolled from Ymffu People＇s Hospital from March of 2015 to October of 2017. Quality- of life was assessed using the Quality- of Life Core Scale developed by the European Cancer Research and Treatment Organization before and during the concurrent ehemoradiotherapy. Results After treatment, the overall health status score of the patients was higher than that before treatment（P 〈 0. 05）. The functional area score was higher than that be- fore treatment（P 〈 0. 05）. In the symptonl field score, the scores of fatigue, nausea, vomiting, pain, loss of appetite and eco- nomic stress were higher than before treatment, and the difference was statistically significant （ P 〈 0. 05 ）. Conclusion After ehemoradiotherapy, the overall quality- of life of patients with nasopharyngeal carcinoma decreased, especially in fatigue, nausea and vomiting, pain, loss of appetite, and economic pressure.