盐酸罗哌卡因复合不同麻醉药物用于硬膜外麻醉临床效果

The Clinical Effect of Ropivacaine Hydrochloride in Epidural Anaesthesia Analyzed by Zoxin, Fentanyl and Fentanyl

目的:将盐酸罗哌卡因分别与佐辛、芬太尼、舒芬太尼复合应用于硬膜外麻醉对其临床效果进行研究分析。方法:选取肇庆市端州区妇幼保健院2011年3月至2014年2月收治的99例实施硬膜外麻醉手术的患者,将其按照随机数字法分为Ⅰ组、Ⅱ组、Ⅲ组各33例。Ⅰ组与佐辛相结合,Ⅱ组与芬太尼相结合,Ⅲ组与舒芬太尼相结合对患者进行硬膜外麻醉手术,观察并比较三组患者进行硬膜外麻醉后在T1(5 min)、T2(10 min)、T3(15 min)、T4(20 min)时患者的舒适度评分(BCS)及视觉模拟评分法(VAS)(疼痛)评分,并记录三组患者手术结束后发生不良反应的情况。结果:Ⅰ组患者麻醉后T1、T2、T3的BCS评分明显高于Ⅱ组、Ⅲ组(P<0.05),VAS评分显著低于Ⅱ组、Ⅲ组(P<0.05);Ⅰ组患者手术结束后的不良反应发生率较其他两组更低(P<0.05)。结论:将盐酸罗哌卡因与佐辛相结合进行硬膜外麻醉手术的治疗效果更佳,手术结束后发生不良反应的几率低,能够使患者的疼痛程度降低。

Objective To study the clinical effects of ropivacaine hydrochloride with dizocine, fentanyl and sufentanil in the clinical effects of epidural anesthesia. Methods A total of 99 patients undergoing epidural anesthesia who were admitted to the Maternal and Child Health Hospital of Duanzhou District, Zhaoqing City, Guangdong Province from March 2011 to February 2014 were randomly divided into Group I, Group II, and Group III. 33 cases. Group I was combined with zoxin, group II was combined with fentanyl, and group III was combined with sufentanil for epidural anesthesia. The comfort scores（BCS） and VAS scores of patients in T1（5 min）, T2（10 min）, T3（15 min）, and T4（20 min） were observed and compared after epidural anesthesia. The adverse reactions occurred in the three groups of patients after the end of surgery were recorded. Results The BCS scores of T1（5 min）,T2（10 min） and T3（15 min） in group I were significantly higher than those in group II and III（P〈0.05）. The VAS score was significantly lower than that in group II and III（P〈0.05）. The incidence of adverse reactions in the patients in group I was lower than in the other two groups（P〈0.05）. Conclusion The combination of ropivacaine hydrochloride and zoicin for epidural anesthesia has a better therapeutic effect, and the incidence of adverse reactions after surgery is low, which can reduce the degree of pain in patients.