炔雌醇环丙孕酮治疗剖宫产术后子宫切口憩室效果分析

Effect of Cyproterone in Treatment of Uterine Incision Diverticulum after Cesarean Section

目的探讨剖宫产术后并发子宫切口憩室的患者应用炔雌醇环丙孕酮药物治疗临床成效。方法方便选择剖宫产术后并发子宫切口憩室的患者80例,均为该院产科2016年2月—2018的2月收治,随机分组,就应用短效避孕药优思明治疗(对照组,n=40)与采用炔雌醇环丙孕酮治疗(观察组,n=40)效果展开对比。结果观察组所收治的剖宫产术后并发子宫切口憩室的患者憩室愈合有效率为87.5%(35/40),对照组为65.0%(26/40),对比差异有统计学意义(χ2=7.314,P<0.05)。在观察组患者月经改善总有效率为97.5%,明显高于对照组77.5%,对比差异有统计学意义(P<0.05)。两组用药治疗前,经期时长经对比差异无统计学意义(t=0.048,P>0.05),停药后均有明显缩短,观察组缩短幅度较对照组更为显著,差异有统计学意义(t=3.738,P<0.05),两组憩室直径在治疗前后均无明显变化,差异无统计学意义(t=0.194,0.000,P>0.05)。两组均无严重不良反应,但观察组胸胀、恶心、头痛等不良反应率为17.5%(7/40),对照组仅为5.0%(2/40),差异有统计学意义(χ2=5.000,P<0.05)。但均可耐受,未出现停药的情况。结论针对临床收治的剖宫产术后并发子宫切口憩室的患者,取炔雌醇环丙孕酮治疗,可显著提高憩室愈合总有效率,增强月经改善效果,缩短经期延长症状,未出现较为严重的不良反应,具一定使用价值。

Objective To investigate the clinical efficacy of ethenoestradiol in patients with uterine incision diverticulum after cesarean section. Methods 80 patients with uterine incision diverticulum complicated by cesarean section were convenient selected. All were obstetrics in the hospital from February 2016 to February 2018. They were randomized and were treated with the short-acting contraceptive drug Yousiming（control group, n=40）. In contrast to the effect of treatment with ethinyl estradiol cyproterone（observation group, n=40）. Results In the observation group, the effective rate of diverticulum healing was 87.5%（35/40） in patients undergoing uterine incision after cesarean section, and 65.0%（26/40） in the control group. The difference was statistically significant（χ^2=7.314, P〈0.05）. The total effective rate of menstruation in the observation group was 97.5%, which was significantly higher than that of the control group（77.5%）, showing a statistically significant difference（P〈0.05）. There was no difference in the menstrual period between the two groups before treatment（t=0.048,P〈 0.05）, which was significantly shortened after discontinuation. The shortening range of the observation group was more significant than the control group, with statistical difference（t=3.738, P〈0.05）, there was no significant difference in diverticulum diameter between the two groups before and after treatment, and there was no statistical difference（t=0.194, 0.000,P〈0.05）. There were no serious adverse reactions in both groups, but the adverse reactions rate of chest bulging, nausea,and headache in the observation group was 17.5%（7/40）, and only 5.0%（2/40） in the control group, with statistical difference（χ^2=5.000, P〈0.05）. But it can be tolerated without stopping the drug. Conclusion For patients with uterine incision diverticulum complicated by uterine incision after clinical cesarean section treatment, taking ethinyl estradiol cyproterone can significantly improve the total effective rate of diverticulum healing, enhance the effect of menstruation, and shorten the symptoms of menstrual extension, without any serious adverse reactions, which has a certain use value.