脑胶质瘤抑瘤因素及其常用治疗研究进展

Tumor-suppressing factors and common treatment of glioma

胶质瘤包括未成行的星形胶质瘤和多形性胶质瘤(glioblastoma multiforme,GBM),是成年人中最常见的恶性脑部肿瘤,占所有脑部肿瘤的50%。其中,GBM是人类脑部肿瘤最常见的恶性肿瘤。GBM的高浸润性,导致它比其他任何脑部肿瘤有更高的死亡率。因此,探索脑胶质瘤抑瘤因素及对应临床治疗对辅助胶质瘤诊疗有较好的推进作用。现对胶质瘤抑瘤因素以及相关治疗进行分析进行综述。

Glioma which includes anaplastic astrocytoma and glioblastoma multiforme（GBM）, is one of the most common malignant brain tumors in adults, accounting for 50% of all brain tumors. GBM is the most common malignant tumor in human brain tumors. High invasion of GBM leads to its higher mortality rate. Therefore, to explore the anti-tumor factors and corresponding clinical treatment of glioma will promote the diagnosis and treatment. In this paper, tumor-suppressing factors and relevant treatment were analyzed and reviewed.