超声诊断单纯性羊水过多与胎儿畸形的相关性研究

Study on the Correlation Between Simple Amniotic Fluid Overload and Fetal Malformation by Ultrasound Diagnosis

目的:探讨超声诊断单纯性羊水过多与胎儿畸形之间的相关性,并对造成羊水过多的胎儿畸形种类进行排序。方法:将我院自2014年8月至2017年8月间进行正常孕检的16~40孕周单纯性羊水过多产妇200例作为研究对象,观察羊水过多胎儿畸形发生率,并对羊水过多组中胎儿畸形种类进行比较排序。结果:研究组羊水指数为24.58±3.26cm,检出胎儿畸形38例,胎儿畸形率为19.00%,对照组羊水指数为13.18±2.74cm,胎儿畸形3例,畸形率1.50%,组间比较差异具有统计学意义(P<0.05);根据解剖结构分类观察到38例畸形胎儿中,神经系统、消化道和骨骼异常占前三位,畸形比例分别为26.32%、21.05%和15.79%,共占63.16%。结论:超声诊断对于单纯羊水过多产妇的胎儿畸形率具有较高的诊断价值,可为患者产前咨询和临床处理提供依据。

Objective： To investigate the correlation between simple amniotic fluid overload and fetal malformation by ultrasound diagnosis,and sort the classification of fetal malformation that leads to amniotic fluid overload. Methods： 200 puerperae with simple amniotic fluid overload at 16 - 40 weeks of gestation,who were under normal gestational examination from August 2014 to August 2017,were selected as the research objects. The incidence of fetal malformation of amniotic fluid overload was observed,and to compare the classification of fetal malformation in the group with amniotic fluid overload.Results： The study group of amniotic fluid index was 24. 58 ± 3. 26 cm,38 cases of fetal malformation,fetal malformation rate was 19. 00%. The control group of amniotic fluid index was 13. 18 ± 2. 74 cm,3 cases of fetal malformation,fetal malformation rate was 1. 50%,the difference was statistically significant（P〈0. 05）. According to the classification of anatomical structures,38 cases of abnormal fetus,the nervous system,digestive tract and skeletal abnormalities accounted for the top three,the rates of malformation were 26. 32%,21. 05% and 15. 79%,accounting for 63. 16%. Conclusion： Ultrasound diagnosis has higher diagnostic value for fetal malformation rate in patients with simple amniotic fluid overload,and can provide the basis for prenatal consultation and clinical treatment.