CT断层扫描联合CD24检测对早期鼻窦癌的诊断价值

Diagnostic Value of CT Tomography Combined with CD24 Detection in the Early Sinus Carcinoma

目的:探讨术前鼻窦CT断层扫描联合CD24检测在鼻窦癌早期诊断中价值。方法:选取2016年1月至2017年12月间我院收治的50例鼻窦癌患者及50例鼻窦炎患者作为本组研究对象;所有患者均采用鼻窦CT断层扫描联合CD24检测,以病理检测作为金标准,分析鼻窦CT断层扫描、CD24单独及联合诊断鼻窦癌的价值。结果:采用CT断层扫描诊断的阳性共48例,CD24检测阳性共51例,平行联合诊断阳性共59例,系列联合诊断阳性共40例;系列联合诊断灵敏度及阴性预测值显著高于各指标单独诊断(P<0.05),平行联合诊断的特异度及阳性预测值显著高于各指标单独诊断(P<0.05);平行联合及系列联合诊断鼻窦癌的ROC曲线下面积显著高于各指标单独诊断(P<0.05)。结论:术前鼻窦CT断层扫描联合CD24检测在对鼻窦癌进行诊断时,可有效提高诊断灵敏度、特异度及诊断效能,具有较高临床应用价值。

Objective： To explore the value of CT tomography and CD24 detection in the early diagnosis of sinus carcinoma. Methods： 50 cases of sinus cancer were selected from January 2016 to December 2017 in our hospital, and 50 cases of sinusitis patients as the object of study of this group; all patients were treated with nasal sinus CT scanning combined with CD24 detection, with the pathological diagnosis as the gold standard, analysis of sinus CT scanning, alone and in combination with the diagnosis of CD24 sinus carcinoma. Results： Using CT computed tomography diagnosis were positive in 48 cases, CD24 positive were 51 cases, parallel combined diagnosis were positive in 59 cases, a series of combined diagnosis were positive in 40 cases; series of sensitivity and negative predictive value of combined diagnosis was significantly higher than that of each index of individual diagnosis（P〈0.05）, the specificity of parallel combined diagnosis and the positive predictive value was significantly higher than that of the diagnosis index alone（P〈0.05）; ROC curve area and series parallel combined joint diagnosis of paranasal sinus carcinoma was significantly higher than the index of individual diagnosis（P〈0.05）. Conclusions： Preoperative CT scan and CD24 detection can improve the diagnostic sensitivity, specificity and diagnostic efficiency, and is of high clinical value.