全程系统化护理联合重组人干扰素治疗肾癌腹腔镜根治术围术期患者的效果观察

Efficacy of perioperative systematic nursing care combined with recombinant human interferon in patients undergoing laparoscopic radical nephrectomy

目的探讨全程系统化护理联合重组人干扰素治疗肾癌腹腔镜根治术围术期患者的临床效果。方法选取2015年3月至2017年9月间上海市同济大学附属第十人民医院收治的拟行肾癌根治术的106例患者作为研究对象进行回顾性分析。将给予围术期全程系统化护理联合重组人干扰素α-2b治疗的57例患者纳入研究组,术后给予重组人干扰素α-2b治疗的49例患者纳入对照组。比较两组患者护理干预前后抑郁及焦虑评分,比较两组患者住院时间、普通饮食时间、退烧时间和白细胞恢复正常时间等临床症状恢复时间,比较两组患者的护理满意度和术后不良反应发生率。结果护理干预前,两组患者的抑郁自评量表(SDS)和焦虑自评量表(SAS)评分比较,差异无统计学意义(P>0.05)。护理干预后,两组患者的SDS和SAS评分均明显低于护理干预前,且研究组明显低于对照组,差异均有统计学意义(均P<0.05)。研究组患者术后住院时间、术后白细胞恢复正常时间、普通饮食时间和退烧时间均明显短于对照组,差异均有统计学意义(均P<0.05)。研究组患者护理满意度为98.2%高于对照组的89.8%,差异有统计学意义(P<0.05)。研究组患者不良反应发生率为3.5%低于对照组患者的12.2%,差异有统计学意义(P<0.05)。结论给予围术期全程系统化护理联合重组人干扰素α-2b治疗肾癌术后患者,可降低患者不良反应发生率,提高患者护理满意度,提高治疗效果,缩短住院时间,改善临床症状恢复情况,值得临床推广。

Objective Research the clinical efficacy of perioperative systematic nursing care combined with recombinant human interferon in patients undergoing laparoscopic radical nephrectomy.Methods Select 106 patients undergoing laparoscopic radical nephrectomy at Shanghai Tenth People＇s Hospital Affiliated to Tongji University between May 2015 and September 2017.They were retrospectively analyzed.Patients receiving fully perioperative systematic nursing care plus recombinant human interferon α-2 b were included in the research group（57 patients） and 49 patients who received recombinant human interferon α-2 b directly after the surgery were included in the control group.Self-rating depression scale（SDS） and Self-rating anxiety scale（SAS） scores before and after nursing intervene,length of hospital stay,ordinary diet time,fever reducing time,time for white blood cells back to normal,nursing satisfaction,incidence of postoperative adverse reactions were compared.Results There was no statistically significant difference in SDS and SAS scores between the two groups pre-intervene.After intervene,the SDS and SAS scores were much lower in both groups than before intervene with the study group lower than the control group（all P〈0.05）.The postoperative length of stay,time for white blood cells back to normal,ordinary diet time and fever reducing time were all much lower in the study group than in the control group（P〈0.05）.The rate of nursing satisfaction was 98.2% for the study group which was higher than 89.80% of the control group（P〈0.05）,The incidence of adverse reaction was 3.5% for the study group which was lower than 12.2%of the control group（P〈0.05）.Conclusion Perioperative systematic nursing care combined with recombinant human interferon α-2 b could reduce adverse reaction,improve patients＇ satisfaction,clinical efficacy,shorten length of hospital stay and improve clinical symptoms of recovery in patients underwent laparoscopic radical nephrectomy,which is worth of clinical promotion.