急性冠状动脉综合征患者采用替格瑞洛治疗的效果分析

Analysis of the Effect of Ticagrelor in the Treatment of Acute Coronary Syndrome

目的探讨急性冠状动脉综合征患者替格瑞洛治疗效果。方法选取2016年6月—2017年5月我院收治的90例急性冠状动脉综合征患者作为研究对象。采用数字表法,将其分为两组。对照组采用氯吡格雷进行治疗,观察组给予替格瑞洛治疗。比较两组患者的治疗效果。结果观察组急性冠状动脉综合征临床干预效果优于对照组,差异具有统计学意义(P<0.05);观察组呼吸困难等并发症发生率高于对照组,差异具有统计学意义(P<0.05);干预后,观察组心功能指标优于对照组,差异具有统计学意义(P<0.05)。结论急性冠状动脉综合征患者替格瑞洛治疗效果确切,可有效改善患者心功能,促进预后转归,但有一定的呼吸系统抑制作用和出血风险,需加强用药监护。

Objective To investigate the effect of ticagrelor in patients with acute coronary syndrome. Methods A total of 90 patients with acute coronary syndrome admitted to our hospital from June 2016 to May 2017 were selected as subjects. The digital table method was used to divide it into two groups. The control group was treated with clopidogrel. The observation group was treated with ticagrelor. The therapeutic effects of the two groups were compared. Results The clinical intervention effect of the observation group was better than that of the control group, and the diference was statistically signifcant （P 〈 0.05）. The incidence of dyspnea and other complications in the observation group was higher than that in the control group （P 〈 0.05）. After intervention, the cardiac function index of the observation group was better than that of the control group, and the diference was statistically signifcant （P 〈 0.05）. Conclusion The treatment effect of ticagrelor in patients with acute coronary syndrome is definite, which can efectively improve the heart function of patients and promote the prognosis. However, there is a certain respiratory inhibition and bleeding risk, and it is necessary to strengthen medication monitoring.