丁苯酞对老年血管性痴呆的疗效及对精神心理量表的影响

The Effect of Butylphthalein on Vascular Dementia in Senile Patients and Its Effect on Mental Scale

目的研究对老年血管性痴呆患者采用丁苯酞治疗的临床效果。方法选取在2017年2月—2018年1月收治的血管性痴呆住院患者共60例作为研究对象。按照随机数字表法,将其均分两组。两组患者均给予基础治疗。观察组在此基础上,采用丁苯酞治疗。对比临床疗效及精神心理状态变化。结果对照组总有效率为66.67%,观察组为86.67%;治疗后观察组CDR、MMSE、ADL分数分别为(0.86±0.25)分、(23.24±3.16)分、(81.64±3.73)分,改善程度均大于对照组,差异均具有统计学意义(P<0.05)。结论丁苯酞可有效提升MMSE评分,对患者的生活能力、精神状况等方面改善效果更佳,可有效改善患者精神心理状态,具有临床价值。

Objective To study the clinical effect of buphthalein in elderly patients with vascular dementia. Methods From February 2017 to January 2018, 60 patients with vascular dementia were selected, and 30 patients were treated with butylphenylphthalein in the basic treatment, compared with the clinical efcacy and mental state. Results The total effective rate of the control group was 66.67%, while that of the observation group was 86.67%. After treatment, the CDR, MMSE and ADL scores of the observation group were （0.86±0.25） points, （23.24±3.16） points and （81.64±3.73） points respectively. The improvement degree of the observation group was higher than that of the control group, and the diference was statistically signifcant （P 〈 0.05）. Conclusion Butylphthalide can effectively improve the MMSE score, the ability to improve the patient＇s life, mental status and other aspects of better efect, can efectively improve the mental state of patients.