双歧三联活菌治疗大面积脑梗死临床疗效

Clinical Effect of Biliary Triple Viable Cell Therapy for Large Area Cerebral Infarction

目的探讨大面积脑梗死患者应用双歧三联活菌肠溶胶囊治疗效果。方法选取我院2017年1月—2018年1月收治的60例大面积脑梗死患者作为研究对象,将其均分为两组,每组各30例。对照组给予早期肠内营养支持治疗,观察组在对照组的治疗基础上,加以双歧三联活菌肠溶胶囊治疗,比较两组治疗前后营养状况、GCS评分和临床疗效。结果两组患者治疗后的血清Hb、TP和ALB水平均显著下降,差异具有统计学意义(P<0.05),GCS评分均显著上升,差异具有统计学意义(P<0.05),组间比较,差异具有统计学意义(P<0.05);观察组患者的治疗总有效率为86.67%,较对照组的66.67%显著提高,差异具有统计学意义(P<0.05)。结论对于大面积脑梗死患者,早期应用双歧三联活菌肠溶胶囊联合肠内营养支持治疗可满足机体营养需求,改善患者预后。

Objective To investigate the therapeutic efect of Bifd Triple Viable enteric coated capsules for patients with large cerebral infarction. Methods 60 patients with massive cerebral infarction were selected from January 2017 to January 2018. They were evenly divided into two groups, 30 cases in each group. The control group was given early enteral nutrition support. The observation group was treated with Bifid Triple Viable enteric coated capsules on the basis of the treatment of the control group. Nutritional status, GCS score and clinical efcacy were compared between the two groups before and after treatment. Results Aft After treatment, the levels of serum Hb, TP and ALB in the two groups were signifcantly decreased （P 〈 0.05）, the GCS scores were signifcantly increased （P 〈 0.05）, and the diferences between the two groups were statistically signifcant （P 〈 0.05）. The total efective rate was 86.67% in the observation group, which was signifcantly higher than 66.67% in the control group （P 〈 0.05）. Conclusion For patients with massive cerebral infarction, early application of bifdobacterium triple enteric-coated capsules combined with enteral nutrition support can meet the nutritional needs of the body and improve the prognosis of patients.