奥拉西坦与高压氧治疗血管性痴呆临床探讨

Oxiracetam and Hyperbaric Oxygen in the Treatment of Vascular Dementia

目的探究奥拉西坦与高压氧联合治疗血管性痴呆的临床效果。方法以我院收治的120例血管性痴呆患者为研究对象,随机将两组患者分为对照组和观察组。对照组单独使用奥拉西坦药物进行治疗,观察组在对照组基础上联合使用高压氧进行治疗,对比两组患者临床疗效的差异。结果观察组总有效率为91.7%,明显优于对照组的75.0%,差异具有统计学意义(P<0.05);观察组智力状态、生活活动能力优于对照组,差异具有统计学意义(P<0.05)。结论奥拉西坦与高压氧联合治疗缺血管性痴呆临床效果显著。

Objective To explore the clinical efficacy of oxiracetam combined with hyperbaric oxygen in the treatment of vascular dementia. Methods 120 patients with vascular dementia in our hospital were randomly divided into two groups： control group and observation group. The control group was treated with oxiracetam alone, and the observation group was treated with hyperbaric oxygen on the basis of the control group. The difference of clinical efficacy between the two groups was compared. Results The therapeutic efficiency of the observation group was 91.7%, obviously superior to 75.0% in the control group, and the difference was statistically significant（P 〈 0.05）. The intelligence state and living activity of the observation group were superior to the control group, and the difference was statistically significant（P 〈 0.05）. Conclusion The clinical effect of the combined treatment of oxacetam and hyperbaric oxygen on vascular dementia was significant.