期刊文献+

1例ALL所致细胞因子释放综合征的护理

Nursing of a Case of Cytokine Release Syndrome Caused by ALL
下载PDF
导出
摘要 急性B淋巴细胞白血病作为恶性血液系统疾病,尽管成年人发病率低,但其危害较大,不容忽视。嵌合抗原受体T细胞治疗本病有一定的价值,但从过去有关报道中可知这种治疗方案处理后容易出现细胞因子释放综合征,影响预后与生存质量,需积极处理。文章就我院收治的1例出现细胞因子释放综合征的成人患者实施了报道。 Acute B-lymphocytic leukemia is a malignant hematological system disease. Despite its low incidence in adults, it is harmful and cannot be ignored. Chimeric antigen receptor T cells have a certain value in the treatment of this disease, but it has been reported in the past that this treatment protocol is prone to cytokine release syndrome after treatment, affecting the prognosis and quality of life, and requires active treatment. This article reported on one case of adult patients with cytokine release syndrome treated in our hospital.
作者 谢丽丽 XIE Lili(Department of Hematology,Affliated Hospital of Xuzhou Medical College,Xuzhou Jiangsu 221000,China)
出处 《中国卫生标准管理》 2018年第17期181-182,共2页 China Health Standard Management
关键词 急性B淋巴细胞白血病 嵌合抗原受体T细胞 细胞因子释放综合征 护理 并发症 预防 acute B lymphocyte leukemia chimeric antigen receptor T cell cytokine release syndrome nursing complications prevention
  • 相关文献

参考文献12

二级参考文献89

  • 1林茜,施姬.护理需要人文关怀[J].中国实用护理杂志,2005,21(11):56-57. 被引量:101
  • 2邵杰,黄晓军,王豪,孙炎,房继莲,马惠,郭芳,饶慧瑛,李晓波,魏来,赵景民.异基因造血干细胞移植术后乙型肝炎的临床特点[J].中华检验医学杂志,2006,29(4):331-334. 被引量:4
  • 3Turtle CJ, Riddell SR. Genetically retargeting CD8 lymphocyte subsets for cancer immunotherapy [ J ]. Curr Opin Immunol, 2011, 23 ( 2 ) : 299-305.
  • 4Terekura S, Yamamoto TN, Gardner RA, etM. Generation of CD19- chimeric antigen receptor modified CD8 T 9ells derived from virus- specific central memory T cells [ J ]. Blood, 2011 119 ( 1 ) : 72-82.
  • 5Shirasu N, Yamada H, Shibaguehi H, et al. Molecular characterization of a fully human chimeric T-cell antigen receptor for tumor-associated antigen EpCAM [ J ]. J Biomed Biotechnol, 2012, 2012: 853-879.
  • 6Shaffer DR, Sayo[do B, Yi Z, ct al. T cells redirected against CD70 for the rmnunotherapy of CD70-positive malignancies [ J ]. Blood, 2011, 117( !6): 4304-4314.
  • 7Gao J, Bematchez C, Sharma P, et al. Advances in the development of cancer immunotherapies [ J ]. Trends Immunol, 2013, 34 ( 2 ) : 90-98.
  • 8Hu WX, Chen HP, Yu K, et al. Gene therapy of malignant solid tumors by targeting erbB2 receptors and by activating T cells [ J ]. Cancer Biother Radiopharm, 2012, 27 ( 10 ) : 711-718.
  • 9SongDG, YeQ, CarpenitoC, etal. In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 ( 4-1BB ) [ J ]. Cancer Res, 2011, 71 ( 13 ) : 4617-4627.
  • 10Song DG, Ye Q, Poussin M, et al. CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo [ J ]. Blood, 2012, 119( 3 ) : 696-706.

共引文献64

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部