重复经颅磁刺激治疗阿尔茨海默病的研究进展

Progress on repetitive transcranial magnetic stimulation for Alzheimer disease

阿尔茨海默病（AD）是一种多发于老年的退行性神经系统疾病，目前机制不明，治疗手段有限。药物治疗因较多不良反应而受到一定限制，因此物理疗法与认知干预成为患者容易接受的治疗方法。近年来一些研究显示重复经颅磁刺激对AD的认知功能和精神行为症状有一定的改善作用，故现对有关进展作一综述。

Alzheimer disease （AD） is a kind of degenerative nervous system disease in elderly patients, with unclear mechanism and limited treatment. Drug therapy is limited by kinds of adverse reactions, so physiotherapy and cognitive intervention becomes a more acceptable treatment for patients. In recent years, some studies show that repetitive transcranial magnetic stimulation （rTMS） can improve the cognitive function, behavior, and psychological symptoms of AD to some extent. Therefore, it is proposed to make a summary of the relevant progress here.