粪便隐血试验在大肠癌诊断中的应用及意义评定

Application of Stool Occult Blood Test in Diagnosing Large Intestinal Carcinoma,and the Ealuation on its Significance

为研究探讨粪便隐血试验在大肠癌诊断中的应用意义,2015年1月至2017年12月,选择就诊于我院的120例疑似大肠癌患者,对患者实施粪便隐血试验,以内镜病理诊断结果为参照,计算粪便隐血试验对大肠癌的诊断灵敏度、特异度、准确率,并采用一致性检验方法,分析粪便隐血试验与内镜病理诊断结果的一致性。结果显示,120例疑似大肠癌患者中,经内镜病理诊断,共确诊86例。以内镜病理诊断结果为参照,粪便隐血试验对大肠癌的诊断灵敏度、特异度、准确率分别为96.51%、97.06%、96.67%。经一致性检验分析,粪便隐血试验与内镜病理诊断结果的一致性系数Kappa值>0.7,诊断结果之间一致性良好。结果表明,采用粪便隐血试验可对大肠癌予以灵敏、准确检出,可作为大肠癌的初步筛查手段。

In order to investigate the application significance of stool occult blood test（SOBT） used in diagnosis of large intestinal carcinoma（LIC）, 120 suspected LIC patients, who were admitted in author＇s hospital from Jan. 2015 to Dec. 2017,were selected to carry out SOBT.Contrasted to the results of endoscopic pathological diagnosis（EPD）, the sensitivity, specificity, and accuracy rate of SOBT for LIC were calulated,and the consistency between SOBT and EPD were analysed by using consistency test.As results,86 of 120 suspected LIC patients were confirmed by EPD.Conirast to which the sensitivity, specificity, and accuracy rate of SOBT for LIC were respectively 96.51%,97.06% and 96.67%.By consistency analysis, between SOBT and EPO,the consistency coefficient kappa value was 〉0.7 ,so there was good consistency between both diagnosis results.Results show that SOBT for inspecting LIC is sensitive and assuracy,and could be used as preliminary screening method for LIC.