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全麻复合硬膜外麻醉对NSCLC切除术患者术后应激反应及肺功能的影响 被引量:16

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摘要 [目的]探讨全麻复合硬膜外麻醉对非小细胞肺癌(NSCLC)切除术患者术后应激反应及肺功能的影响.[方法]在本院接受NSCLC切除术的92例患者随机分为两组,观察组给予全麻复合硬膜外麻醉实施手术,对照组仅实施全身麻醉.比较两组围术期情况、应激反应、肺功能及不良反应.[结果]两组手术时间、麻醉时间比较差异无显著性(P〉0.05),观察组拔管时间、自主呼吸恢复时间、苏醒时间短于对照组,瑞芬太尼用量明显比对照组少(P〈0.05);在术毕、术后2 d时,观察组视觉模拟评分法(VAS)评分、血糖、皮质醇、肾上腺素、去甲肾上腺素均低于对照组(P〈0.05);观察组最大自主通气量(MVV)/第1秒用力呼吸量(FEV1)、[MVV-每分钟静息分钟通气量(VE)]/FEV1明显高于对照组,残气量(RV)/总肺容量(TLC)明显低于对照组(P〈0.05);观察组不良反应总发生率为15.22%(7/46),明显低于对照组的34.78%(16/46)(P〈0.05).[结论]在NSCLC切除术中应用全麻复合硬膜外麻醉效果显著,可有效缓解术后应激反应,对肺功能影响小,且可降低不良反应发生率,临床应用价值高.
出处 《医学临床研究》 CAS 2018年第8期1645-1647,共3页 Journal of Clinical Research
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