磷酸奥司他韦在小儿流感样病例中的临床疗效分析

The Clinical Efficacy of Oseltamivir Phosphate in Infantile Influenza Cases

目的探析磷酸奥司他韦对小儿流感样病例的治疗效果。方法选取75例流感样患儿为研究对象,分为对照组(n=37)及试验组(n=38)。对照组患儿的治疗方法为注射热毒宁,试验组患儿在注射热毒宁的基础上联用磷酸奥司他韦颗粒。将两组患儿临床症状缓解的时间、用药后的不良反应情况和治疗总有效率进行对比分析。结果对照组的不良反应发生率(27.28%)高于试验组(8.34%),差异有统计学意义(P<0.05)。对照组症状缓解的时间长于试验组,且治疗总有效率(77.78%)低于试验组(94.44%),差异有统计学意义(P<0.05)。结论采用磷酸奥司他韦颗粒治疗小儿流感样病例,可加快患儿临床症状的缓解速度,减少用药后的不良反应,治疗效果更好,具有较高的临床应用价值。

OBJECTIVE To explore the effect of oseltamivir on the treatment of infantile influenza-like cases. METHODS Selected 72 children of influenza-like cases as the research object,divided into control groups（ n = 36） and experimental group（ n = 36）Children in the control group were injected with Reduning injection,and children in the experimental group were treated with the oseltamivir phosphate on the basis of the injection of Reduning. The clinical symptoms remission time,adverse reactions and the total treatment efficiency between the two groups were compared. RESULTS The adverse reaction rate（ 27.28%） in the control group was higher than that in the experimental group（ 8.34%）（ P0.05）,the total effective rate of control group（ 77.78%） was lower than that in experimental group（ 94. 44%）. There was significant difference in the data between the groups,which was statistically significant（ P0.05）. CONCLUSION Give influenza-like case children treated with oseltamivir phosphate particles can speed up the relief of clinical symptoms,reduce the adverse reaction of the medicine.The treatment effect is higher,has high clinical value.