庆阳市5693例无偿献血者人类嗜T淋巴细胞病毒的感染情况调查

Investigation of HTLV virus infection in 5 693 volunteer blood donors in Qingyang

目的调查庆阳市无偿献血者人类嗜T淋巴细胞病毒(HTLV)的感染和血清学流行状况,为本市用血安全和血液筛查策略的制定提供理论依据。方法结合已开展的庆阳市无偿献血者血液酶联免疫检测和核酸检测项目,对随机抽检的样本采用双抗原酶免夹心法(ELISA)进行血清学HTLV抗体筛查,初试阳性的标本再进行双孔复试。结果 2017年1月4日-9月30日针对随机抽检的5 693人份庆阳市无偿献血者血液标本,经血清学检测共筛查出HTLV抗体阳性标本4人份,HTLV抗体阳性率为0.07%。结论庆阳市无偿献血者人群中存在一定的血清学HTLV抗体筛查阳性率,为确保血液安全和受血者的健康,有必要扩大监测数量及进行HTLV的确认和追踪研究,为是否将HTLV纳入本市无偿献血者的血液筛查提供科学依据。

Objective To investigate the infection and serological prevalence of human T lymphocyte virus（ HTLV） in volunteer blood donors,so as to provide theoretical basis for the formulation of blood safety and blood screening strategies. Methods Combined with the blood enzyme linked immunosorbent assay and nucleic acid testing project in Qingyang＇s volunteer blood donors,random sampling was used to screen the serological HTLV antibody by enzyme-linked immuno sorbent assay（ ELISA） method,and the specimens with positive initial test were retested by double hole. Results From January 4 to September 30 in 2017 in Qingyang,blood samples of 5 693 volunteer blood donors were randomly selected for serological testing. A total of 4 HTLV antibody-positive specimens were screened,and the positive rate of HTLV antibody was 0. 07%. Conclusion There is a certain positive serological HTLV antibody in the volunteer blood donors in Qingyang. In order to ensure blood safety and the health of blood recipients,it is necessary to expand monitoring and to carry out the identification and tracking of HTLV,so as to provide scientific basis for the integration of HTLV in the blood screening of volunteer blood donors.