甲磺酸去铁胺治疗高血压脑出血60例分析

Analysis of 60 Cases of Hypertensive Cerebral Hemorrhage Treated with Deferoxamine Mesylate

目的分析甲磺酸去铁胺对高血压脑出血患者的效果。方法选取本院2017年1月~2017年12月住院治疗的113例高血压脑出血患者作为研究对象,根据患者住院号奇偶数将分为对照组(53例)与研究组(60例),对照组接受常规治疗,研究组在常规治疗基础上加用甲磺酸去铁胺治疗,观察比较两组患者不同时间(第7天、第14天)相对水肿程度、相对血肿体积以及预后恢复等情况。结果研究组患者第7天、第14天相对血肿吸收量、相对血肿体积均较对照组明显改善,差异有统计学意义(P<0.05);研究组患者在第7天、第14天的NIHSS评分均低于对照组,差异有统计学意义(P<0.05)。结论甲磺酸去铁胺高血压脑出血患者治疗中的应用效果显著,不仅可以减轻患者相对血肿吸收量,而且能够有效缩小相对水肿体积,有助于促进患者神经功能恢复,改善其预后。

Objective To analyze the effect of deferoxamine mesylate on patients with hypertensive intracerebral hemorrhage. Methods A total of 113 patients with hypertensive cerebral hemorrhage admitted to our hospital from January 2017 to December 2017 were enrolled. The patients were divided into the control group （53 cases） and the study group （60 cases） according to the hospitalization number. The control group received rou- tine treatment. The study group was treated with deferoxaanine mesylate on the basis of conventional treatment. The relative edema degree, relative hematoma volume and prognosis recovery were compared between the two groups at different times （day 7 and day 14）. Happening. Results The relative hematoma absorption and relative hematoma volume of the study group were significantly improved compared with the control group on the 7 th and 14 th day, the difference was statistically significant （P〈0.05）. The NIHSS of the study group on the 7 th and 14 th day The scores were low- er than the control group, and the difference was statistically significant （P〈0.05）. Conclusion The application of deferoxamine mesylate in the treatment of hypertensive cerebral hemorrhage is significant, which can not only reduce the relative hematoma absorption, but also effectively reduce the relative edema volume, and help to promote the recovery of neurological function and improve the prognosis of patients.