胆胰疾病患者行治疗性ERCP后生活质量变化分析

Patients with biliary and pancreatic diseases Analysis of the changes of quality of life after therapeutic ERCP

目的明确胆胰疾病患者行治疗性内镜下逆行胆胰管造影术(ERCP)后生活质量改善情况。方法收集2016年1月~2017年12月本院行治疗性ERCP的胆胰疾病患者的病历资料,按年龄将患者分为A、B两组,A组为年龄<75岁患者,B组为年龄≥75岁患者,通过胃肠生活质量评分(GIQLI)量表调查问卷,比较两组患者术前、术后2周生活质量改善情况。结果两组共有203例患者入组,其中A组105例患者,B组98例患者,术后2周A组有7例患者失访,共随访到98例患者,B组术后2周有8例患者失访,共随访到90例患者。A、B两组患者术后2周较术前生活质量无论在自觉症状、生理功能状态、心理状态、社交功能状态及总分均得到改善,比较差异有统计学意义(P<0.01);A、B两组患者术后生活质量改善值组间比较,B组患者在自觉症状和生理功能状态方面较A组患者改善更明显,比较差异有统计学意义(P<0.05)。结论胆胰疾病患者行治疗性ERCP后,术后早期生活质量均可得到改善,且老年患者在自觉症状和生理功能状态方面改善更明显。

Objective To identify improvement of quality of life after therapeutic ERCP for patients with biliary and pancreatic diseases. Methods Collection of medical records of patients with biliary and pancreatic diseases in the Department of Our hospital from January 2016 to December 2017. The patients were divided into two groups at age, A and B, and group A for patients younger than 75 years, and group B for patients equal or greater than 75 years old, The GIQLI questionnaire was used to compare the quality of life of the two groups before and after 2 weeks of operation. Results There were 203 patients in two groups, including 105 patients in group A, 98 patients in group B, 7 patients in 2 weeks after operation in group Awere lost, and 98 patients were followed up; 8 patients in 2 weeks after operation in group B were lost, and 90 patients were followed up. A and B two groups of patients 2 weeks after surgery, compared with preoperative quality of life, whether in symptoms, physical function, emotional dysfunction, social dysfunction and total score in five aspects were improved （P 〈0.01）, A, B two groups of patients postoperative quality of life improvement group comparison, group B patients in symptoms and physical function than group A patients improved more significantly （P〈0.05）. Conclusion After the treatment of ERCE the quality of life in the patients with biliary and pancreatic diseases can be improved at the early stage after operation, and the improvement of the symptoms and physical function of elderly patients is more obvious.