1826例待孕妇女甲状腺功能测定分析

Analysis of 1 826 cases of thyroid function in Preparing pregnant women

目的对甲状腺功能测定在待孕妇女中的应用价值进行评价。方法对2 016年1月~2016年12月溧阳地区参加国家免费孕前优生健康检查的1 826例待孕妇女进行甲状腺功能初筛测定,采用化学发光法测定血清促甲状腺素(TSH),对结果异常者以化学发光法增加血清甲状腺激素(FT4)和抗甲状腺过氧化物酶抗体(TPOAb)检测。结果 1 826例研究对象中,TSH正常的为1 635例(89.53%);TSH异常的为191例(10.46%),其中TPOAb(+)85例(4.66%),甲减59例(3.23%),甲亢47例(2.57%)。根据年龄不同,由小到大分为5组,其中甲功异常检出率最高的是25~29岁年龄组。结论育龄女性有着一定的甲功异常的发病率,待孕妇女进行甲状腺功能测定,很有必要。

Objective To evaluate the value of thyroid function test in pregnant womenprice. Methods From January 2016 to December 2016, 1 826 pregnant women undergoing the National Pre-pregnancy Pregnancy Health Examination in Fuyang District were screened for thyroid function, Chemiluminescence assay was used to measure serum thyroid stimulating hormone （TSH）. Serum thyroid hormone （FT3, FT4） and anti-thyroid peroxidase antibody （TPOAb） were measured by chemiluminescence. Results Among the 1 826 pregnant women who were pregnant, there were 191 cases （accounting for 10.46%） of abnormal TSH, 85 cases of positive TPOAb（4.66%）, 59 cases of hypothyroidism（3.23%）, and 47 cases of hyperthyroidism（2.57%）. The detection rate was different （P 〈 0.01）. Among them, the detection rate of abnormal female work of the pregnant women with the age of 25-29 was the highest. Conclusion Women of child-bearing age have a certain incidence of abnormal A-function. It is necessary for pregnant women to perform thyroid function tests.