急诊重症支气管哮喘并发呼吸衰竭实施无创正压通气对临床结局的影响

Effect of noninvasive positive pressure ventilation on clinical outcome of emergency severe bronchial asthma complicated with respiratory failure

目的探讨急诊治疗重症支气管哮喘并发呼吸衰竭实施无创正压通气的效果。方法将80例急诊重症支气管哮喘并发呼吸衰竭患者根据治疗方式分为传统组(n=40,传统对症急救)和干预组(n=40,无创正压通气辅助对症急救),对比两组的治疗效果。结果干预组总病死率低于传统组(P<0.05)。治疗后,两组的心率(HR)、呼吸频率(RR)、血氧分压(PaO_2)和血氧饱和度(SpO_2)均改善,且干预组优于传统组(P<0.05)。干预组的哮鸣音消失时间、气喘消失时间、血气指标恢复时间及住院时间均短于传统组(P<0.05)。结论急诊治疗重症支气管哮喘并发呼吸衰竭中实施无创正压通气可显著提升疗效,减少病死率,值得推广。

Objective To explore the effect of noninvasive positive pressure ventilation on clinical outcome of emergency severe bronchial asthma complicated with respiratory failure. Methods A total of 80 patients with emergency severe bronchial asthma complicated with respiratory failure were divided into traditional group（n=40, traditional symptomatic first aid） and intervention group（n=40, noninvasive positive pressure ventilation assistant symptomatic first aid） according to the treatment methods. The therapeutic effects of the two groups were compared. Results The total case fatality rate of the intervention group was significantly lower than that of the traditional group（P〈0.05）. After treatment, the heart rate（HR）,respiratory rate（RR）, partial pressure of oxygen（PaO2） and blood oxygen saturation（SpO2） of the two groups improved, and those in the intervention group were better than the traditional group（P〈0.05）. The disappearance time of wheezing sound and asthma, recovery time of blood gas indexes and hospitalization time of the intervention group were shorter than those of traditional group（P〈0.05）. Conclusion Noninvasive positive pressure ventilation in the treatment of emergency severe bronchial asthma complicated with respiratory failure can significantly improve the efficacy and reduce the case fatality rate, which is worthy of promotion.