鼻腔冲洗治疗急、慢性鼻窦炎的临床疗效

Clinical efficacy of nasal irrigation on patients with acute and chronic sinusitis

目的探讨鼻腔冲洗对急、慢性鼻窦炎患者的效果。方法选取2016年9月至2017年9月在我院治疗的100例鼻窦炎患者为研究对象,随机将其分为对照组和观察组,各50例。对照组给予抗生素治疗,观察组在对照组的基础上联合鼻腔冲洗。比较两组患者的症状VAS评分、治疗前、后炎性因子水平及临床疗效。结果观察组患者鼻塞、流涕、咽痛及嗅觉减退VAS评分明显低于对照组(P<0.05)。治疗后,两组患者的IL-6及TNF-α水平均显著降低,且观察组低于对照组(P<0.05)。观察患者的治疗总有效率高于对照组(P<0.05)。结论鼻腔冲洗联合抗生素能够有效改善急、慢性鼻窦炎炎性水平,提高临床有效率,值得临床推广与应用。

Objective To explore the effect of nasal irrigation on patients with acute and chronic sinusitis. Methods From September 2016 to September 2017, 100 patients with sinusitis treated in our hospital were randomly divided into control group and observation group, with 50 cases in each group. The control group was given antibiotic treatment, and the observation group was given nasal irrigation on the basis of the control group. The VAS scores of symptom, the level of inflammatory factors before and after treatment and clinical efficacy were compared between the two groups. Results The VAS scores of nasal obstruction, runny nose, sore throat and olfactory hypothyroidism in the observation group were significantly lower than those in the control group（P〈0.05）. After treatment, the levels of IL-6 and TNF-α in the two groups significantly decreased, and those of the observation group were lower than the control group（P〈0.05）. The total effective rate of the observation group was higher than that of the control group（P〈0.05）. Conclusion Nasal irrigation combined with antibiotics can effectively improve the levels of inflammatory factors in patients with acute and chronic sinusitis, which can improve the clinical efficiency, and it is worthy of clinical promotion and application.