MRI动脉自旋标记技术在脑血管疾病诊断中的应用

Application of Artery Spin Labeling MRI in the Diagnosis of Cerebrovascular Diseases

目的研究MRI动脉自旋标记技术在脑血管疾病诊断中的应用价值。方法收集我院2015年9月至2017年9月155例脑血管疾病患者的病历资料,其中急性脑梗死患者94例,短暂性脑缺血发作患者61例,均在我院接受MRI检查,包括动态磁敏感对比增强灌注成像技术(DSC)与动脉自旋标记技术。采用Bowker检验与Kappa值分析动脉自旋标记技术与DSC各参数的一致性。结果 94例急性脑梗死患者,动脉自旋标记技术与DSC各参数CBF、CBV、MTT、TTP的Bowker值为26.667、26.667、10.333、7.500,Kappa值为0.345、0.345、0.614、0.742。61例短暂性脑缺血发作患者,动脉自旋标记技术与DSC各参数CBF、CBV、MTT、TTP的Bowker值为24.091、24.091、10.800、4.571,Kappa值为0.139、0.139、0.360、0.521。结论MRI动脉自旋标记技术提供的脑血管疾病患者病变区域灌注信息与DSC结果基本相符,可为脑血管疾病诊断提供有价值的信息。

Objective To study the value of artery spin labeling MRI in the diagnosis of cerebrovascular diseases. Methods The clinical data of 155 patients with cerebrovascular diseases who were admitted to the hospital from September 2015 to September 2017 were collected. Among them, there were 94 cases with acute cerebral infarction and 61 cases with transient ischemic attack. All the patients were examined by MRI, including the dynamic susceptibility contrast enhanced perfusion imaging（DSC） and arterial spin labeling technique. The Bowker test and Kappa value were used to analyze the consistency between the arterial spin labeling technique and the DSC parameters. Results For 94 patients with acute cerebral infarction, the Bowker values of arterial spin labeling technique with parameters of DSC CBF, CBV, MTT and TTP were 26.667, 26.667, 10.333 and 7.500, and the Kappa values were0.345, 0.345, 0.614 and 0.742, respectively. For 61 patients with transient ischemic attack, the Bowker values of arterial spin labeling technique with parameters of DSCCBF, CBV, MTT and TTP were 24.091, 24.091, 10.800 and 4.571, and the Kappa values were0.139, 0.139, 0.360 and 0.521, respectively. Conclusion The perfusion information in lesion area of patients with cerebrovascular diseases provided by arterial spin labeling MRI is basically consistent with the results of DSC, and it can provide valuable information for the diagnosis of cerebrovascular diseases.