双能量CT碘含量定量分析在肺实质血流灌注的初步研究

Preliminary Study on the Quantitative Analysis of Iodine with Dual Energy CT for Pulmonary Parenchymal Perfusion

目的评价双能量CT碘含量对正常人肺实质首过血流灌注的定量价值。方法回顾性分析了心肺检查正常的15例患者的首过肺实质血流灌注图像,并进行碘含量的测定,对肺部不同区域的碘含量值进行统计学分析。结果同侧肺相同水平位置腹侧和背侧肺实质血流灌注碘含量值有显著的统计学差异,腹侧的血流灌注碘含量均值低于背侧;左右侧肺相同位置区域肺实质血流灌注碘含量值大部分有统计学差异,左肺的肺实质血流灌注碘含量均值高于右肺(P>0.05)。结论肺实质首过血流灌注的碘含量值可以敏感的反应肺实质不同区域的血流灌注差异。

Objective To evaluate the value for quantitative analysis of the iodine concentration in pulmonary parenchymal with dual-energy CT perfusion imaging. Methods 15 patients without cardiac and pulmonary abnormality were accepted the dual-energy CT scanning. The data was post-processed on Siemens workstation to obtain PBV images, the iodine concentrate were calculated, which of the different area in pulmonary parenchymal were analyzed. Results Mean of iodine content in the ventral was significantly lower than the ipsilateral dorsal lung at same horizontal position; Meanwhile, the mean of iodine content in the left was higher than the right lung at the same horizontal position, however there were no significant differences between the two regions（P〈0.05）. Conclusion The iodine concentrate of PBV is sensitive to the perfusion difference of the pulmonary parenchymal with dual-energy CT perfusion imaging.