CTP＿_(si)map评价卒中易损患者CT灌注成像假阳性的临床价值

The Clinical Value of CT Perfusion＿source Images Maximum Intensity Map in Vulnerable Patients for Stroke with False Positive Results on CT Perfusion

目的评估CT灌注最大密度重建图(CT perfusion_source images maximum intensity map,CTP__(si)map)在卒中易损患者CT灌注成像假阳性中的临床价值。方法回顾性分析2016年5月-2017年10月连续的165例诊断为CT脑局部低灌注的平诊患者,根据患者的CTP__(si)map将其分成无侧支循环组(真阳性)及有侧支循环组(假阳性),将有侧支循环形成的"假阳性"病例筛选出来,进行误判率统计。结果通过CTP__(si)map判别CT灌注成像脑局部低灌注的真实性,其中真阳性(无侧支循环组)55例,假阳性(有侧支循环组)110例,误判率66.67%。结论传统CT灌注成像结合CTP__(si)map可以更准确地判断侧支循环形成情况,对卒中易损患者的诊断及指导临床治疗具有重要的临床应用价值。

Objective To evaluate the clinical value of CT perfusion_source images maximum intensity map（CTP__（si）map） in vulnerable patients for stroke with false positive results on conventional CT perfusion.Methods 165 consective outpatients diagnosed with hypoperfusion on CTP from Beijing Tiantan hospital from May 2016 to October 2017 were included in this study. All the patients were divided into two groups according to CTP__（si）map： true positive group（without collateral circulation） and false positive group（with collateral circulation）. The false positive cases were screened, and the misjudgment rate was calculated.Results The actual condition of chronic local cerebral hypoperfusion on CTP was finally judged by CTP__（si）map. The result showed that true positive group had 55 cases and false positive group had 110 cases. The misjudgment rate was as high as 66.67%.Conclusions CTP__（si）map can improve accuracy in assessing collateral circulation, which is valuable to diagnose vulnerable patients for stroke and guide therapeutic options.