血清降钙素原、血小板、乳酸的检测对判断脓毒血症患者临床预后的意义

The clinical outcomes of serum procalcitonin,blood platelet and lactic acid in patients with sepsis

目的探讨降钙素原(PCT)、血小板(PLT)、血乳酸(LAC)对脓毒症患者预后判断的临床意义。方法选取2010年1月至2016年12月在普宁市人民医院ICU确诊为脓毒血症的112例病例进行分析。根据28d生存率分为A组:好转组(病情治愈或病情好转,转出ICU至普通病房),有88例;B组:恶化组(死亡及病情明显恶化),有24例。记录相关资料并收集入科时血清PCT、PLT、LAC水平。结果 A、B两组入科基本情况比较,差异无统计学意义(P>0.05);进行两组间比较,B组PCT、LAC水平明显高于A组,差异有统计学意义(P<0.05);B组PLT明显低于A组,差异有统计学意义(P<0.05)。结论脓毒血症预后好转患者的血清PCT、LAC水平明显低于预后恶化患者,脓毒血症预后好转患者的血清PTL水平明显高于预后恶化患者,血清PCT、PLT、LAC可作为评估脓毒血症患者预后的指标。

Objective To explore the prognostic significance of serum procalcitonin（PCT）,blood platelet（PLT）and lactic acid（LAC）in patients with sepsis.Methods A total of 112 patients diagnosed as sepsis in the ICU in our hospital from January 2010 to December 2016 were selected.According to 28 days survival rate,they were divided into group A：improving group（illness cured or improved,turn out of the ICU to ordinary ward）,88 cases;Group B：deterioration group（death and obvious deterioration）,there were 24 cases.Record and collect the relevant data into the ICU department of PCT,PLT,LAC level.Results A,B two groups of patients in ICU department when the basic situation of no statistical significance（P〉0.05）;Compared between the two groups,PCT,LAC level of B group was obviously higher than that in group A（P〈0.05）,while PLT was lower and progressively decreased（P〈0.05）.Conclusion Improve prognosis of patients with PCT,LAC level is lower than the deterioration of the patients prognosis,while PLT is lower.PCT,PLT and LAC can predict the prognosis of patients with sepsis.