参杞归陈汤联合肺康复治疗对稳定期慢阻肺患者预后及生活质量影响的研究

Effects of Shenqi Guichen decoction combined with pulmonary rehabilitation on prognosis and quality of life in patients with stable chronic obstructive pulmonary disease

目的:探讨参杞归陈汤联合肺康复治疗对稳定期慢阻肺患者预后及生活质量的影响。方法:选取稳定期慢阻肺患者120例,根据治疗方法不同分成两组,对照组给予沙美特罗替卡松粉吸入剂及茶碱缓释片治疗,研究组给予参杞归陈汤联合肺康复治疗,对比两组患者治疗后六分钟步行实验结果、肺功能改善情况及SGRQ圣乔治呼吸问卷评分结果。结果:治疗后研究组患者的六分钟步行实验中,Ⅰ级有28例,Ⅱ级有13例,Ⅲ级有11例,Ⅳ级有8例,分别占46.7%、21.7%、18.3%、13.3%,对照组中,Ⅰ级有29例,Ⅱ级有14例,Ⅲ级有11例,Ⅳ级有6例,分别占48.3%、23.3%、18.3%、10.0%(P<0.05);治疗前两组患者的肺功能状况无明显区别(P>0.05),治疗后研究组患者的FEV1(%)为(49.1±13.3),FEV1/预计值(%)为(59.7±13.5),PVC(%)为(53.0±11.5),对照组患者的FEV1(%)为(49.1±12.0),FEV1/预计值(%)为(52.1±14.0),PVC(%)为(52.3±11.8)(P<0.05);治疗前两组患者SGRQ圣乔治呼吸问卷评分结果无显著差异(P>0.05),治疗后两组患者SGRQ圣乔治呼吸问卷评分均有明显改善(P<0.05)。结论:稳定期慢阻肺患者在治疗时应采用参杞归陈汤联合肺康复治疗能够明显改善患者肺的各项功能指标,提高稳定期慢阻肺患者的生活质量,促进患者的进一步康复。

Objective： To investigate the effects of Shenqi Guichen decoction combined with pulmonary rehabilitation on prognosis and quality of life in patients with stable chronic obstructive pulmonary disease. Methods：120 patients with stable COPD patients as the research object,according to the different treatment methods were divided into two groups,the control group was given to Salmeterol Xinafoate and Fluticasone Propionate powder for inhalation and Theophylline Sustained-release tablets treatment,study group received oral administration of Salmeterol Xinafoate and Fluticasone Propionate powder for inhalation combined with pulmonary rehabilitation,compared two groups of patients after six minites walk test results,improve lung function and respiratory questionnaire score of St Georges SGRQ.Results： In the six minite walking experiment of the patients after treatment,there were 28 in grade I,13 in grade II,11 in grade III and 8 in grade IV,46.7%,21.7%,18.3% and 13.3% in the control group. There was no significant difference in lung function between the two groups before the treatment （ P 〉0.05）. The FEV1 （%） of the patients in the study group was （49.1±13.3）,the expected value of FEV1/ （%） was （59.7±13.5）,PVC （%） was （53 ＋）,FEV1 （%） of the control group was （49.1±12）,and the FEV1/ expected value （%） was （52.1±14）. PVC （52.3%） was （52.3±11.8） （ P 〈0.05）,and there was no significant difference in the results of SGRQ St Georges respiratory questionnaire in the two groups before treatment （ P 〉0.05）. The scores of the respiratory questionnaire in the two groups after the treatment were significantly improved.Conclusion：The patients with chronic obstructive pulmonary disease in the stable period should adopt Shenqi Guichen decoction combined with lung rehabilitation therapy can obviously improve the functional indexes of the patients＇ lung,it can improve the quality of life of the patients with the stable stage of the lung and promote the further rehabilitation of the patients. Key words Pulmonary disease,chronic obstructive /integrated Chinese traditional and western medicine therapy Rehabilitation Quality of life