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分娩方式对瘢痕子宫再次妊娠产妇产后应激状态及母婴结局的影响 被引量:2

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摘要 目的探讨不同分娩方式对瘢痕子宫再次妊娠产妇产后应激状态及母婴结局的影响。方法对我院1 894例瘢痕子宫再次妊娠产妇临床资料进行回顾性分析,根据其分娩方式分为阴道分娩组(A组,n=703)和剖宫产组(B组,n=1 191)。比较两组产妇产前1天(T1)及产后1天(T2)时应激反应指标[皮质醇(Cor)、血管紧张素Ⅱ(Ang-Ⅱ)、去甲肾上腺素(NE)]、急性时相反应蛋白(APRP)[前白蛋白(PA)、C反应蛋白(CRP)、α1-抗胰蛋白酶(α1-AT)、]及血清细胞因子[白介素-6(IL-6)、转化生长因子β1(TGF-β1)、肿瘤坏死因子α(TNF-α)]水平,观察母婴结局。结果T2时,两组Cor、Ang-Ⅱ、NE、CRP、α1-AT、IL-6、TGF-β1、TNF-α水平均较T1时升高,PA水平则均较T1时降低,且A组变化幅度小于B组(P均<0.05)。A组产妇产时出血量、产褥病率均、新生儿住院时间均小于B组,Apgar评分则大于B组(P均<0.05)。结论瘢痕子宫再次妊娠产妇阴道分娩相对于剖宫产对产妇应激状态和炎性状态影响较小,于母婴健康有利,仔细评价母婴健康状态、严格掌握适应证和禁忌证后可作为首选分娩方案。
作者 陈颂
出处 《福建医药杂志》 CAS 2018年第4期87-90,共4页 Fujian Medical Journal
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