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阿帕替尼引起支气管-食管瘘一例 被引量:4

Apatinib damages trachea-esophageal fistula in 1 case
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摘要 患者,男,喉癌术后1年余,喉癌复发,放疗后4个月,PET-CT提示喉癌复发,化疗1个疗程后,二次复发,化疗2个疗程后,二次进展,行相关靶向治疗,服用甲磺酸阿帕替尼片1个月后,出现支气管-食管瘘。 A male patient was suffered by laryngeal carcinoma recurrence diagnosed by PET-CT after 4 months of radiotherapy. After 1 course of chemotherapy, the lm'yngeal carcinoma recurred ; after 2 course of chemotherapy, the symptom progressed. The patient was given related target therapy. After takingapatinib for a month, the patients suf- fered trachea-esophageal fistula.
作者 梁晓宇 苗秋丽 张越 张四喜 LIANG Xiao-yu;MIAO Qiu-li;ZHANG Yue;ZHANG Si-xi(Department of Pharmacy,the First Hospital of Jilin University,Changchun 130021,China)
出处 《实用药物与临床》 CAS 2018年第9期1085-1086,共2页 Practical Pharmacy and Clinical Remedies
关键词 阿帕替尼 支气管-食管瘘 喉癌 不良反应 Apatinib Trachea-esophageal fistula Laryngeal carcinoma Adverse reaction
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