中药保留灌肠联合清热消痈汤治疗急性单纯性阑尾炎临床疗效观察

Clinical Observation of Chinese Medicine Retains Enema Combined with Qingre Xiaoyong Decoction on the Treatment of Acute Simple Appendicitis

目的：探讨中药保留灌肠联合清热消痈汤治疗急性单纯性阑尾炎的临床疗效观察。方法：收集我院收治的急性单纯性阑尾炎患者100例,随机分为对照组和治疗组,各50例,对照组予以甲硝唑注射液及氨苄西林注射液;治疗组在对照组的基础上给予中药灌肠联合清热消痈汤治疗,两组患者均治疗4周。比较4周后两组患者的临床疗效、血清C反应蛋白（CRP）及肿瘤坏死因子（TNF-α）水平、体温恢复正常时间、腹痛及压痛减轻时间、白细胞计数及中性粒细胞百分比。结果：治疗组临床总有效率为86.00%,对照组临床总有效率为50.00%,治疗组较对照组改善显著,两组结果具有显著差异（P〈0.05）;治疗组治疗后血清C反应蛋白（CRP）及肿瘤坏死因子（TNF-α）水平较对照组降低明显,结果具有显著差异（P〈0.05）;治疗组治疗后患者体温恢复正常时间、腹痛及压痛减轻时间均短于对照组,结果有显著差异（P〈0.05）;治疗组患者白细胞计数及中性粒细胞百分比降低较对照组明显,结果具有显著差异（P〈0.05）。结论：中药保留灌肠联合清热消痈汤针对急性阑尾炎具有较好的治疗作用,可起到解热镇痛、通腑泻下、清热凉血的功效,值得临床推广应用。

Objective：To explore the curative effect of Chinese medicine retains emema combined with Qingre Xiaoyong Decoction on the treatment of acute simple appendicitis. Methods：Selected 100 cases of acute single appendicitis treated in our hospital,randomly divided into control group and treatment group,50 cases in each group,the control group was treated with metronidazole injection and ampicillin injection. The treatment group based on the control group treated on the application of Chinese medicine retains emema combined with Qingre Xiaoyong Decoction,two groups were treated for 4 weeks. Compared the clinical curative effect of two groups after 4 weeks,serum C-reactive protein（CRP）and tumor necrosis factor（TNF-α）levels,body temperature returned to normal time,abdominal pain and tenderness,reduce time,the percentage of white blood cells and neutrophils cells. Results：The total clinical curative effect of the treatment group was 86.00%,the total clinical curative effect of the control group was 50.00%,compared with the control group,the treatment group was better than control group,the difference was statistically significant（P〈0.05）;After treatment,serum C-reactive protein（CRP） and tumor necrosis factor（TNF-α）of the treatment group significantly lower than those in the control group,the difference was statistically significant（P〈0.05）;The normal time of body temperature recovery,abdominal pain and tenderness in the treatment group were shorter than the control group,the difference was statistically significant（P〈0.05）;Compared with the control group,the percentage of white blood cells and neutrophils in the treatment group decreased significantly than the control group,the difference was statistically significant（P〈0.05）. Conclusion：Chinese medicine retains emema combined with Qingre Xiaoyong Decoction treating acute appendicitis has good treatment effect,have antipyretic and analgesic effect,clearing hollow viscera and making diarrh,clearing heat and cooling blood,worthy of clinical popularization and application.