针刺联合中药复方郁乐疏对卒中后抑郁患者抑郁症状和神经功能康复的影响

Effects of Acupuncture Combined with Chinese Herbal Compound Yuleshu on Depressive Symptoms and Neurological Rehabilitation of Patients with Post-stroke Depression

目的：探讨针刺联合中药复方郁乐疏对卒中后抑郁患者抑郁症状和神经功能康复的影响。方法：收集我院收治的卒中后抑郁患者94例,随机分为对照组和治疗组各47例,对照组予以阿米替林片;治疗组在对照组的基础上给予针刺联合中药复方郁乐疏制剂,两组患者均治疗4周。比较两组患者临床疗效、汉密尔顿（HAMD）17项抑郁量表评分、神经功能缺损评分及中医证候积分。结果：治疗组临床总有效率为80.85%,对照组临床总有效率为57.44%,治疗组较对照组疗效明显,两组结果具有显著差异（P〈0.05）;与对照组相比,治疗组患者的汉密尔顿（HAMD）17项抑郁量表分数降低的更为显著,两组结果具有差异性（P〈0.05）;与对照组相比,治疗组患者神经功能缺损评分改善较为明显,两组结果具有差异性（P〈0.05）;治疗组的中医症状积分明显低于对照组（P〈0.05）,表明治疗组在改善中医临床症状方面疗效明显优于对照组。结论：针刺联合中药郁乐疏对卒中后抑郁患者症状和神经功能康复具有较好的临床治疗效果,可起到疏肝解郁、调畅气机、疏通经脉、促进神经功能改善恢复的功效,值得临床推广应用。

Objective：To explore the effects of acupuncture combined with Chinese herbal compound Yuleshu on depressive symptoms and neurological rehabilitation of patients with post-stroke depression. Methods：Collected 94 cases of poststroke depression patients of our hospital,were randomly divided into control group and treatment group,47 cases in each group,the control group was treated with amitriptyline tablets;the treatment group was given acupuncture combined with Chinese herbal compound Yuleshu. Compared the clinical efficacy of two groups of patients,Hamilton（HAMD）17 depression scale scores,neurologic defect and TCM syndrome integrals. Results：The clinical total effective rate of treatment group was 80.85%,and control group was 57.44%,the treatment group was better than the control group. There was significant difference between the two groups（P〈0.05）;Compared with the control group,Hamilton 17 depression scale（HAMD）scores of the treatment group reduced more significantly,there was significant difference between the two groups（P〈0.05）;Compared with the control group,the improvement of neurologic defect was obviously in the treatment group. There was significant difference between the two groups（P〈0.05）. The TCM symptom score of the treatment group was significantly lower than the control group（P〈0.05）. It showed that the curative effect of treatment group was better than the control group in improving the clinical symptoms of TCM. Conclusion：Acupuncture combined with Chinese herbal compound Yuleshu had a good clinical effect on the symptoms and neurological function of poststroke depression. It can be a function of dredging the liver,regulating Qi activity,dredging the meridians and promoting the recovery of nerve function. It is worthy of clinical application.