中国大气颗粒物污染与致癌研究进展

Research progress on ambient particulate matter pollution and carcinogenesis in China

室外空气污染和污染空气中的颗粒物是一类致癌物,而近年中国的大气颗粒物污染仍然维持在较高浓度水平。通过综述中国近年大气颗粒物污染现状和开展的颗粒物致癌机制研究,分析中国研究中颗粒物有关实验动物致癌性的证据和颗粒物致癌的人群流行病学线索,阐述大气颗粒物与癌症的关系,提出中国亟需开展相关研究。

In recent years the concentration of ambient air particulate matter（PM） has remained high in China; however the International Agency for Research on Cancer（IARC） has classified that the outdoor air pollution and the particulate matter in outdoor air pollution are carcinogenic to humans. This article summarizes the current situation of PM pollution in China and reviews the research progress on the mechanism of PM carcinogenesis and the evidences given by China＇s toxicologic studies and epidemiological studies on PM carcinogenicity in the past decades. The article suggests that China should urgently conduct researches to confirm the relationship between PM and cancers and that a series of actions should be taken to alleviate China＇s air pollution.