经尿道钬激光剜除和等离子电切术治疗良性前列腺增生的对比研究

Transurethral Holmium Laser Ablation and Plasma Resection for Benign Prostatic Hyperplasia

目的比较经尿道钬激光前列腺剜除术(HOLEP)与等离子前列腺电切术(PKRP)治疗良性前列腺增生(BPH)的效果。方法方便选取2017年1—12月收治该院的60例BPH患者随机分入两组,每组30例,分别进行HOLEP或PKRP手术治疗。比较两组术中情况、术后疗效及并发症发生情况。结果钬激光组手术时间较长(P<0.05),但术中出血量(55.54±36.21)m L、膀胱冲洗时间(15.58±3.21)h,均低于电切组(P<0.05);钬激光组切除组织量(53.23±15.84)g,多于电切组(P<0.05)。术后3个月IPSS、Qo L评分、残余尿量(PVR)及并发症差异无统计学意义(P>0.05),钬激光组的最大尿流率Qmax(18.38±5.21)m L/s,优于电切组(P<0.05)。结论经尿道钬激光剜除术治疗前列腺增生,安全、有效、创伤小,前列腺组织切除彻底,具有推广价值。

Objective To compare the efficacy of transurethral holmium laser enucleation of the prostate（HOLEP） and plasma resection of the prostate（PKRP） in the treatment of benign prostatic hyperplasia（BPH）. Methods 60 patients with BPH admitted to the hospital from January to December in 2017 were convenient selected and randomized into two groups. 30 patients in each group were treated with HOLEP or PKRP. The intraoperative conditions, postoperative efficacy, and complications were compared between the two groups. Results The holmium laser group had a longer operation time（P〈0.05）,but the intraoperative blood loss（55.54±36.21）mL and bladder irrigation time（15.58±3.21） h were lower than that of the TUR group（P〈0.05）. The amount of tissue（53.23±15.84）g was more than that of the transection group（P〈0.05）. There were no significant differences in IPSS, Qo L scores, residual urine volume（PVR） and complications after 3 months（P〉0.05）. The maximum urinary flow rate Qmax（18.38±5.21）mL/s in the He-Ne laser group was superior to that of the TUR group（P〈0.05）. Conclusion Transurethral holmium laser ablation for the treatment of benign prostatic hyperplasia is safe, effective,minimally invasive, and the prostate tissue is removed completely.