诺和锐30联合二甲双胍治疗2型糖尿病患者的临床疗效分析

Analysis of Clinical Curative Effect of Novomix30 Combined with Melbine in Treatment of Patients with Type 2 Diabetes

目的探析对2型糖尿病患者采取诺和锐30联合二甲双胍治疗的临床效果。方法选取2017年9月—2018年4月期间在该院就诊的60例诊断为2型糖尿病的患者,将其随机分为治疗组和对照组,各为30例患者,其中,对照组采取诺和灵30R联合二甲双胍,治疗组采取诺和锐30联合二甲双胍治疗,比较两组治疗后效果、血糖变化及低血糖发生率等情况。结果治疗组治疗后空腹血糖水平(5.53±1.11)mmol/L、餐后2 h血糖水平(9.64±1.03)mmol/L、糖化血红蛋白水平(6.24±1.22)%与对照组比较差异有统计学意义(t=4.396,4.109,4.018,P<0.05);治疗组血糖达标时间(4.89±1.32)d显著低于对照组(8.53±1.34)d,比较差异有统计学意义(t=4.227,P<0.05);治疗组低血糖发生率3.23%(1/30)显著低于对照组23.23%(7/30),比较差异有统计学意义(χ~2=5.236,P<0.05)。结论对2型糖尿病患者采取诺和锐30联合二甲双胍治疗的临床效果明显,能够更好的改善患者血糖水平,减少低血糖发生,值得临床推广。

Objective To study the clinical effect of novomix30 combined with melbine in treatment of patients with type 2 diabetes.Methods 60 cases of patients with type 2 diabetes diagnosed in our hospital from September 2017 to April 2018 were selected and randomly divided into two groups with 30 cases in each,the control group were treated with novolin 30 R combined with melbine,while the treatment group were treated with novomix30 combined with melbine,and the treatment effect,changes of blood glucose and incidence rate of hypoglycemia were compared between the two groups.Results After treatment,the fasting blood glucose level,postprandial 2 h blood glucose level and glycosylated hemoglobin level in the treatment group were respectively（5.53 ±1.11）mmol/L,（9.64 ±1.03） mmol/L and（6.24 ±1.22）%,and the differences between groups were obvious,（t =4.396,4.109,4.018,P 0.05）;the blood glucose standards-reaching time in the treatment group was obviously lower than that in the control group [（4.89±1.32） d vs（8.53±1.34）d],and the differences were obvious（t=4.227,P〈0.05）;the incidence rate of hypoglycemia in the treatment group was obviously lower than that in the control group [3.23%（1/30） vs 23.23%（7/30）],and the difference was obvious（χ2=5.236,P〈0.05）.Conclusion The clinical effect of novomix30 combined with melbine in treatment of patients with type 2 diabetes is obvious,which can better improve the blood glucose level and reduce the occurrence of hypoglycemia,and it is worth clinical promotion.