黄金微针射频治疗面部痤疮瘢痕的疗效评估

Evaluation of efficacy of microneedling radiofrequency for the treatment of facial acne scars

目的评价黄金微针射频治疗面部痤疮瘢痕的有效性及安全性。方法广州市皮肤病防治所2016年6月至2017年6月采用黄金微针射频治疗的42例痤疮瘢痕患者（观察组）和CO：点阵激光治疗的47例痤疮瘢痕患者（对照组），分别用疗效四级单盲法和临床痤疮瘢痕评估量表（ECCA）权重评分对两组治疗前后照片分析统计，评估疗效。统计方法采用r检验，两独立样本t检验及配对资料Wilcoxon秩和检验。结果治疗后，观察组和对照组总体有效率分别为92．9％（39例）和89．4％（42例），两组差异无统计学意义（χ^2=0．042，P〉0．05）。治疗前观察组ECCA权重评分为46．7±16．3，对照组为45．7±15．8，两组差异无统计学意义（t=0．271，P〉0．05）。治疗后，观察组ECCA权重评分降低为29．5±15．1，前后比较差异有统计学意义（z=-5．713，P〈0．05）；对照组降低为31,3±14．9，前后比较差异有统计学意义（Z=-6．086，P〈0．05）。结论黄金微针治疗面部痤疮瘢痕疗效确切，安全性高且创伤小。

Objective To evaluate the efficacy and safety of microneedling radiofrequency in the treatment of facial acne scars. Methods A retrospective study was conducted. According to the inclusion and exclusion criteria, 42 patients with acne scars receiving microneedling radiofrequency treatment （observation group） and 47 patients with acne scars treated with fractional CO2 laser （control group） in Guangzhou Institute of Dermatology were enrolled into this study from June 2016 to June 2017. Single-blind evaluation was conducted according to a four-grade scoring system and ECCA grading scale （6chelle d＇6valuation clinique des cicatrices d＇acn6） by two clinically experienced dermatologists to evaluate and compare the clinical efficacy between the 2 groups, based on the clinical photos before and after the treatment. Statistical analysis was done by using ehi-square test, t test of two independent samples and paired Wilcoxon signed rank test. Results After treatment, no significant difference in the total response rate was observed between the observation group （92.9%, 39 cases） and control group （89.4%, 42 cases; χ2 = 0.042, P 〉 0.05）. Before the treatment, there was no significant difference in the ECCA score between the observation group （46.7 ± 16.3） and control group （45.7 ± 15.8, t = 0.271, P 〉 0.05）. After the treatment, the ECCA score in the observation group and control group significantly decreased into 29.5± 15.1 and 31.3 ±14.9 respectively （Z =-5.713,-6.086, respectively, both P 〈 0.05）. Conclusion Microneedling radiofrequency is effective for the treatment of facial acne scars, with high safety and less injuries.