摘要
膀胱癌是泌尿系统最常见的恶性肿瘤,具有高复发率和高死亡率的特点,其发病机制尚不完全清楚。此外临床上缺乏合适的分子生物标志物用于早期诊断、预后评估、药物反应评估等。本文将围绕膀胱癌的发病机制、分子生物标志物研究以及新的治疗方式进展等方面进行综述。
Bladder cancer (BC) is the most common malignant tumor of the urinary system, which is associated with high recurrence and mortality rate. The pathogenesis of BC is not yet completely clear, and it' s difficult to find suitable biomarkers for early detection, evaluation of prognosis, and surveillance of drug responses. In this article, we will discuss the pathogenesis of bladder cancer, molecular biomarkers and the newest therapy category.
作者
程帆
Cheng Fan(Department of Urology,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2018年第9期1591-1594,共4页
Chinese Journal of Experimental Surgery
关键词
膀胱癌
发病机制
分子生物标志物
免疫治疗
个体化治疗
Bladder cancer
Pathogenesis
Molecular biomarkers
Immunotherapy
Individualized treatment