儿童偏头痛血清神经元特异性烯醇化酶水平的研究

Study on serum neuron specific enolase level in children with migraine

偏头痛(migraine)是儿童神经内科的一种常见疾病,病因及发病机制尚不清楚,最近的研究提出偏头痛在反复发作的基础上可能导致神经细胞的损伤,而并不是以往人们认为的的一种良性功能性疾病。神经元特异性烯醇化酶(NSE)作为中枢神经元损伤的标志物,不仅可以反映神经胶质细胞和神经元的损伤,还可以初步评估神经损伤的程度。本研究目的在于探讨儿童偏头痛血清神经元特异性烯醇化酶水平,以期进一步了解偏头痛的发病机制及是否存在脑损伤,对偏头痛的进一步治疗提供依据。

Migraine is a common disease in children＇s neurology.The etiology and pathogenesis are still unclear.Recent studies suggest that migraine may cause nerve cell damage on the basis of recurrent episodes.A benign functional disease considered.Neuron specific enolase （NSE）,a marker of central neuronal damage,can not only reflect the damage of glial cells and neurons,but also initially assess the extent of nerve damage.The purpose of this study was to investigate children＇s migraine serum.Neuron specific enolase levels,in order to further understand the pathogenesis of migraine and the presence of brain damage,provide a basis for further treatment of migraine.