摘要
目的:优选橘红挥发油的提取及β-环糊精包合的最佳工艺。方法:以挥发油的提取量为考察指标,采用正交试验优选挥发油提取工艺;以挥发油包合率为考察指标,优选β-环糊精包合工艺。结果:挥发油最佳提取工艺为:加10倍量的水,浸泡30min,提取8h;挥发油包合的最佳工艺为:采用饱和水溶液法,挥发油与β-环糊精的用量比为1∶10,包合温度50℃,包合时间2h。结论:优选的橘红挥发油提取工艺提油率较高,包合工艺稳定可行。
Objective： To optimize the process of volatile oil extraction and β -cyclodextrin （ β-CD） inclusion from exocarpium citri rubrum. Methods： Taking the extraction of volatile oil as an investigation index, the extraction process of volatile oil is selected by orthogonal test, and the inclusion rate of volatile oil is used as an index to optimize the inclusion process of β -cyclodextrin. Results： The best optimized extraction conditions were： adding 10 times the amount of water, soaking 30min, extracting 8h. The best optimal inclusion conditions were： using saturated aqueous solution method, the ratio of volatile oil to β-cyclodextrin was 1 ： 10, the inclusion temperature was 50℃, and the inclusion time was 2h. Conclusion： The optimized extraction technology has a high rate of oil yield. The optimized inclusion technology is stable and feasible.
作者
张海鸣
范斌
费超
闫明
彭娟
聂颖兰
闫寒
ZHANG Hai-ming;FAN Bin;FEI Chao;YAN Ming;PENG Juanl;NIE Yin-lanl;YAN Han(Experimental Research Center,China Academy of Chinese Medical Sciences,Beijing 100700,China;State Key Laboratory Breeding Base of Dao-di Herbs,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization,Beijing Normal University,Beijing 100875,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2018年第9期4155-4157,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
中央级公益性科研院所基本科研业务费专项资金(No.zz2017007),中央本级重大增减支项目(No.2060302)
关键词
橘红
挥发油
Β-环糊精
包合工艺
提取工艺
正交试验
Exocarpium crtri rubrum
Volatile oil
β -cyclodextrin
Inclusion technology
Extraction technology
Orthogonal test
