循时调经联合饮食运动干预对多囊卵巢综合征血清激素水平的影响

The Effect of Time-Based Menstrual Conditioning Combined With Diet Exercise Invention on Serum Hormone Levels in Endomorphy Type Polycystic Ovary Syndrome Patients

目的:探讨循时调经联合饮食运动干预对肥胖型多囊卵巢综合征(PCOS)患者血清激素水平的影响。方法:选取肥胖型PCOS患者82例,随机均分为治疗组和对照组两组。对照组实施饮食运动干预,治疗组在对照组基础上采取中医循时调经进行干预。对比两组体格检查结果、脂糖代谢情况及血清激素水平。结果:干预后两组体质量、体质量指数(BMI)、腰围均明显低于干预前(P<0.05),且治疗组均较对照组低(P<0.05);干预后两组总胆固醇(TC)与甘油三酯(TG)等脂代谢指标及空腹血浆葡萄糖(FPG)、空腹血浆胰岛素(FINS)等糖代谢指标水平均明显低于干预前(P<0.05),且治疗组均较对照组低(P<0.05);干预后两组促卵泡刺激素(FSH)、促黄体生成素(LH)与总睾酮(T)等血清激素水平均明显低于干预前(P<0.05),且治疗组均低于对照组(P<0.05)。结论:对肥胖型PCOS患者采取循时调经联合饮食运动进行干预,可显著减轻患者体质量,明显改善患者糖脂代谢指标,有效降低其血清激素水平。

Objective： To investigate the effect of time-based menstrual conditioning combined with diet exercise invention on serum hormone levels in endomorphy type polycystic ovary syndrome（PCOS） patients. Methods： A total of 82 cases of endomorphy type PCOS patients were randomly divided into two groups, the observation group and the control group. The control group was given diet exercise intervention, while the observation group was intervened by time-based menstrual conditioning on the basis of the control group. The results of physical examination, lipid and glucose metabolism and serum hormone levels were compared between the two groups. Results： After intervention, the weight, body mass index（BMI） and waist circumference of the two groups were significantly lower than those before intervention（P〈0.05）, and the observation group was lower than the control group（P〈0.05）. After intervention, the indexes of lipid metabolism such as total cholesterol（TC） and triglyceride（TG） and the indexes of glycometabolism such as fasting plasma glucose（FPG） and fasting plasma insulin（FINS） were significantly lower than those before intervention（P〈0.05）, and the observation group was lower than the control group（P〈0.05）. After intervention, the levels of serum hormones such as follicle stimulating hormone（FSH）, luteinizing hormone（LH） and total testosterone（T） in the two groups were significantly lower than those before intervention（P〈0.05）, and the observation group were lower than the control group（P〈0.05）. Conclusion： The intervention on the endomorphy type PCOS patients by time-based menstrual conditioning combined with diet exercise can significantly reduce the weight of the patients, improve the index of glycolipid metabolism and reduce the level of serum hormone.